不同吞咽时期大脑皮质激活特征：基于功能性近红外光谱技术

doi:10.3969/j.issn.1006-9771.2024.06.011

Abstract

Abstract:

Objective To explore the cerebral cortex activation in different swallowing periods using functional near-infrared spectroscopy (fNIRS).

Methods From October to December 2023, a total of 18 healthy adults were recruited to perform four tasks of visual stimulation, chewing, tongue tip sliding and repeated swallowing during fNIRS acquisition, to calculate the cortical activation β values covering a total of 41 channels in frontal, parietal and occipital lobes.

Results During the preoral period, the bilateral pre-motor and supplementary motor cortex (PSMC), bilateral inferior prefrontal gyrus, right visual association cortex (AVC), and left primary motor cortex (PMC) were significantly activated (P < 0.05). During oral preparation, the right pars triangularis (PTG), right frontal polar area (FPA), right dorsolateral prefrontal cortex (DPC), left primary somatosensory cortex (PSC), left PSMC and left PMC were significantly activated (P < 0.05). During the transition between oral and pharyngeal phases, bilateral PSMC and bilateral PMC were significantly activated (P < 0.05). Bilateral PSC, bilateral PTG, bilateral FPA, bilateral orbitofrontal area, bilateral PSMC, bilateral DPC and bilateral PMC were significantly activated during two consecutive periods of oral and pharyngeal phases (P < 0.05).

Conclusion The swallowing movement requires the coordination of the frontal, parietal and occipital cortex. The main activated brain areas are different in different swallowing stages, and the PSMC and PMC are involved in most swallowing stages.

Key words: swallow, functional near-infrared spectroscopy, cerebral cortex

CLC Number:

R338

LIU Jiaqi, HOU Shanshan, WANG Xinyu, ZHU Chongtian, WANG Xiaowen. Characteristics of cerebral cortex activation in different swallowing periods based on near-infrared spectroscopy[J]. Chinese Journal of Rehabilitation Theory and Practice, 2024, 30(6): 709-718.

Figures/Tables 11

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通道	S-D	MNI坐标			Brodmann 分区	左/右	脑区	β	P值
通道	S-D	X	Y	Z	Brodmann 分区	左/右	脑区	β	P值
1	S1-D1	60	-5	46	6	右	PSMC	0.099±0.185	0.040
3	S2-D2	53	44	-12	47	右	IPG	0.067±0.067	< 0.001
11	S5-D4	-52	44	-14	47	左	IPG	0.050±0.439	< 0.001
15	S7-D1	51	-5	56	6	右	PSMC	0.039±0.043	0.001
18	S7-D13	41	-4	64	6	右	PSMC	0.031±0.035	0.002
28	S11-D5	-61	-3	44	6	左	PSMC	0.044±0.041	< 0.001
29	S11-D11	-51	-1	56	6	左	PSMC	0.029±0.024	< 0.001
31	S12-D13	30	-4	70	6	右	PSMC	0.030±0.023	< 0.001
32	S13-D11	-42	-24	68	4	左	PMC	0.037±0.027	< 0.001
33	S13-D14	-32	-22	75	4	左	PMC	0.025±0.026	< 0.001
34	S14-D11	-41	0	63	6	左	PSMC	0.030±0.023	< 0.001
35	S14-D14	-30	1	68	6	左	PSMC	0.042±0.052	0.003
36	S15-D15	31	-89	35	19	右	AVC	0.066±0.076	0.002

通道	S-D	MNI坐标			Brodmann 分区	左/右	脑区	β	P值
通道	S-D	X	Y	Z	Brodmann 分区	左/右	脑区	β	P值
4	S2-D7	59	31	4	45	右	PTG	0.150±0.187	0.003
7	S3-D8	28	69	3	10	右	FPA	0.066±0.061	< 0.001
13	S6-D5	-62	-27	51	3	左	PSC	0.064±0.053	< 0.001
14	S6-D11	-53	-26	62	3	左	PSC	0.063±0.091	< 0.001
19	S8-D2	48	55	1	46	右	DPC	0.129±0.123	< 0.001
20	S8-D7	52	41	19	45	右	PTG	0.128±0.139	< 0.001
21	S8-D8	38	60	18	46	右	DPC	0.098±0.110	< 0.001
22	S9-D3	5	72	3	10		FPA	0.051±0.038	< 0.001
23	S9-D8	17	69	20	10	右	FPA	0.040±0.044	< 0.001
28	S11-D5	-61	-3	44	6	左	PSMC	0.108±0.094	< 0.001
29	S11-D11	-51	-1	56	6	左	PSMC	0.056±0.059	< 0.001
32	S13-D11	-42	-24	68	4	左	PMC	0.038±0.037	< 0.001
33	S13-D14	-32	-22	75	4	左	PMC	0.048±0.048	< 0.001
34	S14-D11	-41	0	63	6	左	PSMC	0.036±0.033	< 0.001
35	S14-D11	-30	1	68	6	左	PSMC	0.050±0.052	< 0.001

通道	S-D	MNI坐标			Brodmann 分区	左/右	脑区	β	P值
通道	S-D	X	Y	Z	Brodmann 分区	左/右	脑区	β	P值
1	S1-D1	60	-5	46	6	右	PSMC	0.037±0.042	0.002
15	S7-D1	51	-5	56	6	右	PSMC	0.048±0.055	0.040
17	S7-D12	41	-27	69	4	右	PMC	0.037±0.029	0.002
18	S7-D13	41	-4	64	6	右	PSMC	0.044±0.034	< 0.001
28	S11-D5	-61	-3	44	6	左	PSMC	0.054±0.055	< 0.001
29	S11-D11	-51	-1	56	6	左	PSMC	0.048±0.053	< 0.001
30	S12-D12	31	-25	74	4	右	PMC	0.036±0.033	< 0.001
31	S12-D13	30	-4	70	6	右	PSMC	0.017±0.020	< 0.001
32	S13-D11	-42	-24	68	4	左	PMC	0.050±0.048	< 0.001
33	S13-D14	-32	-22	75	4	左	PMC	0.036±0.031	< 0.001
34	S14-D11	-41	0	63	6	左	PSMC	0.049±0.048	< 0.001
35	S14-D14	-30	1	68	6	左	PSMC	0.044±0.054	0.003

通道	S-D	MNI坐标			Brodmann 分区	左/右	脑区	β	P值
通道	S-D	X	Y	Z	Brodmann 分区	左/右	脑区	β	P值
2	S1-D6	62	-30	52	1	右	PSC	0.039±0.028	< 0.001
4	S2-D7	59	31	4	45	右	PTG	0.108±0.110	< 0.001
5	S3-D2	38	64	-12	11	右	OFA	0.040±0.035	< 0.001
6	S3-D3	15	71	-12	11	右	OFA	0.023±0.020	< 0.001
7	S3-D8	28	69	3	10	右	FPA	0.027±0.021	< 0.001
8	S4-D3	-9	72	-11	11	左	OFA	0.046±0.043	< 0.001
9	S4-D4	-32	66	-12	11	左	OFA	0.040±0.041	< 0.001
10	S4-D9	-20	72	4	10	左	FPA	0.038±0.029	< 0.001
13	S6-D5	-62	-27	51	3	左	PSC	0.045±0.043	< 0.001
14	S6-D11	-53	-26	62	3	左	PSC	0.043±0.044	< 0.001
15	S7-D1	51	-5	56	6	右	PSMC	0.052±0.052	< 0.001
16	S7-D6	52	-27	63	3	右	PSC	0.037±0.026	< 0.001
17	S7-D12	41	-27	69	4	右	PMC	0.035±0.029	< 0.001
18	S7-D13	41	-4	64	6	右	PSMC	0.040±0.031	< 0.001
19	S8-D2	48	55	1	46	右	DPC	0.063±0.048	< 0.001
20	S8-D7	52	41	19	45	右	PTG	0.038±0.035	< 0.001
21	S8-D8	38	60	18	46	右	DPC	0.036±0.035	< 0.001
22	S9-D3	5	72	3	10		FPA	0.040±0.052	0.004
23	S9-D8	17	69	20	10	右	FPA	0.022±0.022	< 0.001
25	S10-D4	-47	56	3	46	左	DPC	0.037±0.038	< 0.001
26	S10-D9	-34	60	20	46	左	DPC	0.039±0.046	0.002
27	S10-D10	-54	39	19	45	左	PTG	0.041±0.043	0.001
28	S11-D5	-61	-3	44	6	左	PSMC	0.065±0.055	< 0.001
31	S12-D13	30	-4	70	6	右	PSMC	0.023±0.019	< 0.001
32	S13-D11	-42	-24	68	4	左	PMC	0.068±0.070	< 0.001
34	S14-D11	-41	0	63	6	左	PSMC	0.044±0.047	< 0.001
35	S14-D14	-30	1	68	6	左	PSMC	0.036±0.033	< 0.001

Characteristics of cerebral cortex activation in different swallowing periods based on near-infrared spectroscopy

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