多通道功能性电刺激结合任务导向训练对脑卒中上肢偏瘫患者脑功能网络的即刻影响

doi:10.3969/j.issn.1006-9771.2024.04.012

Abstract

Abstract:

Objective To observe the change of brain functional network of stroke patients with upper limb hemiplegia during task-oriented training under multi-channel functional electrical stimulation (FES) using functional near-infrared spectroscopy (fNIRS).

Methods From April to October, 2023, 15 stroke inpatients with upper limb hemiplegia were selected from the First People's Hospital of Yancheng. They accepted task-oriented training, under real stimulation and sham stimulation determined with tossing a coin, with an interval of a day. The real stimulation was induced with multi-channel FES, and sham stimulation was induced with no stimulation. During the training, fNIRS was used to measure the concentrations of oxygenated hemoglobin in the bilateral prefrontal cortex (PFC), premotor cortex (PMC), supplementary motor area (SMA) and sensorimotor cortex (SMC), to obtain the overall functional connectivity and the difference of functional connectivity based on region of interest.

Results Compared with the sham stimulation, the overall functional connectivity reduced (t = -2.735, P< 0.05); the functional connectivity between the contralesional PFC to ipsilateral PFC, and the contralesional PFC to contralesional PMC also reduced (P< 0.05) under real stimulation.

Conclusion Multi-channel FES combined with task-oriented training can optimize the cortical functional connectivity in stroke patients with upper limb hemiplegia.

Key words: stroke, multi-channel functional electrical stimulation, task-oriented training, functional near-infrared spectroscopy, brain functional network

CLC Number:

R743.3

CHEN Yuanyue, LI Jiabin, KUAI Feng, PENG Lili, XIANG Jie. Immediate effect of multi-chancel functional electrical stimulation combined with task-oriented training on brain functional network in stroke patients with upper limb hemiplegia[J]. Chinese Journal of Rehabilitation Theory and Practice, 2024, 30(4): 462-467.

Figures/Tables 3

References 33

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项目	量值
性别(男/女)/n	12/3
年龄/岁	60.6±6.96
病程/d	39(23, 238)
卒中类型(梗死/出血)/n	11/4
损伤侧(左/右)/n	7/8
FMA-H评分	7.53±2.64
MMSE评分	28.33±1.99

Immediate effect of multi-chancel functional electrical stimulation combined with task-oriented training on brain functional network in stroke patients with upper limb hemiplegia

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