不同电极经颅直流电刺激对脑卒中上肢功能康复的效果

doi:10.3969/j.issn.1006-9771.2023.05.005

Abstract

Abstract:

Objective To observe the clinical efficacy of anodal or cathodal transcranial direct current stimulation (atDCS and ctDCS) on upper limb function of stroke patients with moderate to severe upper extremity impairment.

Methods From January to September, 2022, 69 patients in Zhongda Hospital Southeast University were randomly divided into control group (n = 23), atDCS group (n = 23) and ctDCS group (n = 23). All the groups received conventional rehabilitation. Moreover, atDCS group received atDCS over the M1 area of the affected hemisphere, ctDCS group received ctDCS over the M1 area of the unaffected hemisphere, and the control group received placebo stimulation. Before and four weeks after treatment, they were assessed with Fugl-Meyer Assessment-Upper Extremities (FMA-UE), Wolf Motor Function Test (WMFT) and modified Barthel index (MBI).

Results Before treatment, there was no significant difference in the scores of FMA-UE, WMFT and MBI among groups (F < 1.165, P > 0.05). After treatment, all the scores improved significantly in all the groups (|t| > 6.412, P < 0.001), and were higher in the atDCS group and ctDCS group than in the control group (P < 0.05), however, no significant difference was found between the atDCS group and ctDCS group (P > 0.05).

Conclusion Both atDCS and ctDCS could improve the upper limb motor function and activities of daily living of stroke patients with moderate to severe upper extremity impairment.

Key words: stroke, transcranial direct current stimulation, upper limb

CLC Number:

R743.3

CAI Qian, XU Liang, YANG Xi, LIU Jin, MA Ming. Effect of anodal or cathodal transcranial direct current stimulation on upper limb function of stroke patients[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2023, 29(5): 521-526.

Figures/Tables 4

References 37

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组别	n	性别(男/女)/n	年龄/岁	病程/d	偏瘫侧别(左/右)/n	卒中类型(脑出血/脑梗死)/n
对照组	23	12/11	53.00±12.91	135.70±25.79	8/15	6/17
阳极组	23	10/13	55.04±13.47	142.22±25.04	10/13	8/15
阴极组	23	11/12	51.09±12.86	131.78±21.63	9/14	7/16
χ²/F值		0.340	0.526	1.089	0.365	0.411
P值		0.840	0.593	0.342	0.833	0.814

组别	n	治疗前	治疗后	t值	P值
对照组	23	21.57±2.81	26.30±2.87	-6.412	< 0.001
阳极组	23	21.26±3.14	35.17±2.73^a	-18.913	< 0.001
阴极组	23	22.22±3.49	35.48±3.12^a,b	-11.843	< 0.001
F值		0.551	73.881
P值		0.579	< 0.001

组别	n	治疗前	治疗后	t值	P值
对照组	23	17.17±3.17	22.87±3.27	-7.130	< 0.001
阳极组	23	17.83±2.29	31.87±2.75^a	-21.750	< 0.001
阴极组	23	18.48±3.15	31.30±2.88^a,b	-16.248	< 0.001
F值		1.165	66.041
P值		0.318	< 0.001

组别	n	治疗前	治疗后	t值	P值
对照组	23	30.39±3.97	56.57±3.44	-26.455	< 0.001
阳极组	23	30.30±4.63	69.17±2.79^a	-39.078	< 0.001
阴极组	23	30.17±3.30	68.52±3.84^a,b	-41.444	< 0.001
F值		0.017	101.362
P值		0.983	< 0.001

Effect of anodal or cathodal transcranial direct current stimulation on upper limb function of stroke patients

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