Bcl-2/Bax与脊髓损伤

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《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2009, Vol. 15 ›› Issue (12): 1147-1149.

• 综述 • Previous Articles Next Articles

Bcl-2/Bax and Spinal Cord Injury(review)

XIONG Liu-bo,YANG Zheng,XU Yan,et al

Chengdu Medical College, Chengdu 610081, Sichuan, China

Received:2009-07-13 Published:2009-12-25 Online:2009-12-25

Abstract

Abstract: Apoptosis play an important role in the process of secondary spinal cord injury(SCI). Bcl-2 is a multigene family, which have fifteen members. Bcl-2 and Bcl-xL can inhibit apoptosis, but Bax, Bad, Bak, and Bcl-xS can promote apoptosis. Bcl-2 and Bax is the most representative gene in Bcl-2 gene family, Bcl-2/Bax determine cells whether goes to die. In this paper, we reviewed the latest developments in Bcl-2/Bax adjustment for SCI.

Key words: spinal cord injury, Bax, Bcl-2, medicine, transgenic, neurenergen

XIONG Liu-bo;YANG Zheng;XU Yan;et al. Bcl-2/Bax and Spinal Cord Injury(review)[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2009, 15(12): 1147-1149.

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Bcl-2/Bax and Spinal Cord Injury(review)

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