《中国康复理论与实践》

《中国康复理论与实践》 ›› 2004, Vol. 10 ›› Issue (01): 53-54.

• 临床康复 • 上一篇    下一篇

局部亚低温治疗急性脑出血的临床研究

张磊1; 梅元武1; 肖荣华2   

  1. 1.华中科技大学同济医学院协和医院神经内科 湖北武汉市 430022;2.华中科技大学同济医学院协和医院中医科 430022
  • 收稿日期:2003-09-25 出版日期:2004-01-25 发布日期:2004-01-25

Clinical study of locally moderate hypothermia on treating acute intracerebral hemorrhage

ZHANG Lei, MEI Yuan-wu, XIAO Rong-hua   

  1. Department of Neurology, Union Hospital, Tongji Medical College of Huazhong University of Science Technology, Wuhan 430022, Hubei,China
  • Received:2003-09-25 Published:2004-01-25 Online:2004-01-25

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摘要： 目的观察冰帽加双侧颈动脉区冰敷治疗急性脑出血的临床疗效和探讨最佳治疗时机。方法174例急性脑出血患者随机分为治疗组和对照组,每组87例。对照组给予常规治疗,治疗组在常规治疗的基础上同时给予亚低温治疗;治疗组中46例在发病3小时内治疗,41例在发病3小时后治疗。观察治疗组与对照组以及治疗组中发病3小时内与发病3小时后两组的临床疗效和预后情况。结果亚低温治疗组与对照组比较,神经功能改善(P<0.05),生存率及恢复良好率提高(P<0.05)。发病3小时内开始治疗者优于3小时后开始者(P<0.05)。结论亚低温治疗能有效减轻急性脑出血后的神经功能缺损,降低病死率和致残率;最佳治疗时机在发病3小时以内。

关键词: 亚低温, 治疗, 急性脑出血

Abstract: ObjectiveTo demonstrate the effect of moderate hypothermia and doule carotid ice applied to acute intracerebral hemorrhage (ICH) and the best opportunity of treatment.Methods174 cases with ICH were randomly divided into treated group and control group, 87 cases for each group. Each case of both groups was treated by routine therapy, moreover, all cases in treated group were treated by moderate hypothermia (MHT).The clinical effect and prognosis between treated group and control group were contrasted,so to do between the cases in the treated group who were treated no more than 3 hours and more than 3 hours after attack.ResultsCompared with the control group, the neurological function improved in the treated group(P<0.05), as well as survival rate and recovery(P<0.05).Cases who treated no more than 3 hours after attack was better than that of more than 3 hours(P<0.05).ConclusionModerate hypothermia can effectively ease the neurologic deficits after ICH, decrease mortality and disable rate.The best therapy time is within 3 hours after ICH.

Key words: moderate hypothermia, treatment, acute intracerebral hemorrhage