脱水剂在急性脊髓损伤中的应用进展

doi:10.3969/j.issn.1006-9771.2018.04.001

《中国康复理论与实践》 ›› 2018, Vol. 24 ›› Issue (4): 373-377.doi: 10.3969/j.issn.1006-9771.2018.04.001

• 专题:中枢神经损伤后水肿的机制及干预 • 下一篇

脱水剂在急性脊髓损伤中的应用进展

张超^{1, 3, 4}, 李建军^{1, 3, 4}, 杨德刚^{1, 3, 4}, 杨明亮^{1, 3, 4}, 杜良杰^{1, 3, 4}, 张文豪^{1, 3, 4}, 刘长彬^{1, 3, 4}, 李大鹏^{1, 3, 4}, 胡安明¹, 秦川^{1, 3, 4}

1.首都医科大学康复医学院,北京市 100068;
2.中国康复研究中心北京博爱医院,a.脊柱脊髓神经功能重建科;
b.神经外科,北京市 100068;
3.北京脑重大疾病研究院神经损伤与修复研究所,北京市 100068;
4.北京市神经损伤与康复重点实验室,北京市 100068

收稿日期:2017-12-18 修回日期:2018-01-27 出版日期:2018-04-25 发布日期:2018-04-27
通讯作者: 李建军。E-mail: crrc100@163.com
作者简介:张超(1989-),男,汉族,山东临沂市人,博士研究生,主要研究方向：脊柱脊髓损伤的康复与治疗。
基金资助:
1.中央级公益性科研院所基本科研业务费专项资金项目(No. 2016CZ-4); 2.中国康复研究中心课题(No. 2012-1; No. 2013-7)

Application Progress of Dehydrating Agent in Acute Spinal Cord Injury (review)

ZHANG Chao^{1, 3, 4}, LI Jian-jun^{1, 3, 4}, YANG De-gang^{1, 3, 4}, YANG Ming-liang^{1, 3, 4}, DU Liang-jie^{1, 3, 4}, ZHANG Wen-hao^{1, 3, 4}, LIU Chang-bin^{1, 3, 4}, LI Da-peng^{1, 3, 4}, HU An-ming¹, QIN Chuan^{1, 3, 4}

1. Capital Medical University School of Rehabilitation Medicine, Beijing 100068, China;
2. a. Department of Spinal and Neural Function Reconstruction, b. Department of Neurosurgery, Beijing Bo'ai Hospital, China Rehabilitation Research Center, Beijing 100068, China;
3. Center of Neural Injury and Repair, Beijing Institute for Brain Disorders, Beijing 100068, China;
4.Beijing Key Laboratory of Neural Injury and Rehabilitation, Beijing 100068, China

Received:2017-12-18 Revised:2018-01-27 Published:2018-04-25 Online:2018-04-27
Contact: LI Jian-jun. E-mail: crrc100@163.com

摘要/Abstract

摘要： 急性脊髓损伤(ASCI)可分为原发性损伤和继发性损伤。脊髓水肿对脊髓继发性损伤的发展至关重要。脊髓水肿主要分为细胞毒性水肿和血管源性水肿。脱水剂在ASCI后水肿的治疗中作用明显。本文主要介绍甘露醇、高渗盐水、甘油果糖、呋塞米、人血白蛋白、白藜芦醇等脱水剂在ASCI治疗中的应用进展。

关键词: 脊髓损伤, 水肿, 脱水剂, 综述

Abstract: Acute spinal cord injury (ASCI) can be divided into primary injury and secondary injury. Spinal cord edema is important for the development of secondary injury after ASCI. Spinal cord edema can be mainly divided into cytotoxic edema and angioedema. The application of dehydrating agents in the treatment of acute spinal cord injury is obvious. This article described the application of mannitol, hypertonic saline, glycerol fructose, furosemide, human serum albumin, resveratrol and other dehydrating agents in the treatment of ASCI.

Key words: spinal cord injury, edema, dehydrating agent, review

中图分类号:

R651.2

张超, 李建军, 杨德刚, 杨明亮, 杜良杰, 张文豪, 刘长彬, 李大鹏, 胡安明, 秦川. 脱水剂在急性脊髓损伤中的应用进展[J]. 《中国康复理论与实践》, 2018, 24(4): 373-377.

ZHANG Chao, LI Jian-jun, YANG De-gang, YANG Ming-liang, DU Liang-jie, ZHANG Wen-hao, LIU Chang-bin, LI Da-peng, HU An-ming, QIN Chuan. Application Progress of Dehydrating Agent in Acute Spinal Cord Injury (review)[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2018, 24(4): 373-377.

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脱水剂在急性脊髓损伤中的应用进展

Application Progress of Dehydrating Agent in Acute Spinal Cord Injury (review)

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