《中国康复理论与实践》

《中国康复理论与实践》

• 临床研究 • 上一篇    下一篇

脑性瘫痪患儿运动康复期间相关生化指标的变化①

王巍巍，庞伟，康贝贝，范艳萍，孙颖，李鑫   

  1. 佳木斯大学附属第三医院，佳木斯大学康复医学院，黑龙江佳木斯市154003。
  • 出版日期:2016-05-25 发布日期:2016-07-04

Changes in Biochemistry in Cerebral Palsy Children during Rehabilitation Exercise

WANG Wei-wei, PANG Wei, KANG Bei-bei, FAN Yan-ping, SUN Ying, LI Xin   

  1. The Third Affiliated Hospital of Jiamusi University, Rehabilitation College of Jiamusi University, Jiamusi, Heilongjiang154003, China
  • Published:2016-05-25 Online:2016-07-04

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摘要： 目的探讨脑瘫患儿生化指标与运动康复训练的关系。方法2015 年3~11 月，24 例脑瘫患儿于治疗前测量血红蛋白、肌酸激酶、尿素，常规运动疗法训练，分别于治疗1 周增加运动负荷后和6 周后再次测量。治疗前和治疗6 周后采用粗大运动功能测量量表(GMFM-88)进行评定。结果两组治疗后GMFM-88 评分显著增高(t>7.12, P<0.001)。血红蛋白、肌酸激酶和血尿素均在训练后1 周明显升高(P<0.01)；6 周后血红蛋白和血尿素基本回到治疗前水平(P˃0.05)，肌酸激酶有所降低(P<0.01)，但仍高于治疗前水平(P<0.01)。结论血红蛋白、肌酸激酶和血尿素可以反映小周期、阶段康复训练情况，揭示运动训练负荷对脑瘫患儿身体的影响。

关键词: 脑性瘫痪, 康复, 运动疗法, 血红蛋白, 肌酸激酶, 血尿素

Abstract: Objective To investigate the variability in biochemistry in cerebral palsy children who accepted rehabilitation exercise. Methods From March to November, 2015, 24 children with cerebral palsy were measured the levels of hemoglobin, creatine kinase and blood urea before treatment. They all accepted routine rehabilitation exercise, and were measured hemoglobin, creatine kinase and blood urea again one week after treatment as the load increased, and six weeks after treatment at the end of exercise. They were assessed with Gross Motor Function Measure (GMFM-88) before and six weeks after treatment. Results The scores of GMFM-88 improved after treatment (t>7.12, P<0.001). Hemoglobin decreased (P<0.01), while creatine kinase and blood urea increased one week after treatment (P<0.01). Hemoglobin and blood urea came back to the levels before treatment six weeks after treatment (P˃0.05), while creatine kinase reduced (P< 0.01), but was still more than that before treatment (P<0.01). Conclusion Hemoglobin, creatine kinase and blood urea may respond the training situation of cycle and the stage of exercise, and indicate the effects of load in the cerebral palsy children accepted rehabilitation exercise.

Key words: cerebral palsy, rehabilitation, physical therapy, hemoglobin, creatine kinase, blood urea