《中国康复理论与实践》

《中国康复理论与实践》 ›› 2015, Vol. 21 ›› Issue (09): 1074-1077.

• 基础研究 • 上一篇    下一篇

低频重复经颅磁刺激对脑卒中后记忆及认知功能的影响

芦海涛，孙莉，郭华珍，张通
  

  1. 作者单位：1.首都医科大学康复医学院，北京市 100068；2.中国康复研究中心博爱医院神经康复科，北京市 100068。
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2015-09-25 发布日期:2015-09-25

Effect of Low-frequency Repetitive Transcranial Magnetic Stimulation on Memory and Cognition Impairment after Stroke

LU Hai-tao, SUN Li, GUO Hua-zhen, ZHANG Tong
  

  1. 1. Capital Medical University School of Rehabilitation Medicine, Beijing 100068, China; 2. Department of Neurorehabilitation, Beijing Bo'ai Hospital, China Rehabilitation Research Center, Beijing 100068, China
  • Received:1900-01-01 Revised:1900-01-01 Published:2015-09-25 Online:2015-09-25

PDF (PC)

被引次数

19

摘要： 目的 观察低频重复经颅磁刺激(rTMS)刺激右侧前额叶背外侧皮层对脑卒中患者认知及记忆功能的影响。方法 脑卒中后记忆功能障碍患者40例，随机分为磁刺激组(n=19)和假刺激组(n=21)，分别接受真假1 Hz rTMS治疗。所有患者在治疗前、治疗结束后和治疗结束2个月后分别用蒙特利尔认知评估量表(MoCA)中文版、洛文斯顿作业疗法认知评估(LOTCA)及行为记忆量表(RBMT)进行测评。结果 两组在治疗后及治疗结束2个月时，MoCA、LOTCA及RBMT评分均有显著升高(P<0.001)，磁刺激组改善程度明显优于假刺激组(P<0.01)。结论 低频rTMS可以改善脑卒中后认知及记忆功能障碍。

关键词: 脑卒中, 重复经颅磁刺激, 记忆, 认知

Abstract: Objective To investigate the effects of low-frequency repetitive transcranial magnetic stimulation (rTMS) on post-stroke disfunction of cognition and memory by stimulating right dorsolateral prefrontal cortex. Methods 40 patients were randomized into the rTMS (n=19) and sham (n=21) groups. The function of cognition and memory were measured before treatment, after treatment and 2 months post-treatment with Montreal Cognitive Assessment (MoCA), Loewenstein Occupational Therapy Cognitive Assessment (LOTCA) and Rivermead Behaviour Memory Test (RBMT). Results All scores improved in both groups after treatment and 2 months post-treatment (P< 0.001), and improved more in the rTMS group than in the sham group (P<0.01). Conclusion Low-frequency rTMS may improve the function of memory and cognition after stoke.

Key words: stroke, repetitive transcranial magnetic stimulation, memory, cognition