《中国康复理论与实践》

《中国康复理论与实践》 ›› 2015, Vol. 21 ›› Issue (05): 501-504.

• 特稿 • 上一篇    下一篇

内皮型一氧化氮合酶与缺血性脑血管病

朱艳含，罗勇   

  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2015-05-25 发布日期:2015-05-25

Endothelial Nitric Oxide Synthase and Ischemic Cerebrovascular Disease (review)

ZHU Yan-han, LUO Yong   

  1. Department of Neurology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China
  • Received:1900-01-01 Revised:1900-01-01 Published:2015-05-25 Online:2015-05-25

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被引次数

5

摘要： 内皮型一氧化氮合酶(eNOS)及其产物一氧化氮(NO)可以调节缺血性脑血管疾病发作后血流量的恢复，抑制炎症反应的发生以及促进神经血管的再生；eNOS基因多态性与缺血性脑血管病的发生有着密切联系。本文就eNOS与缺血性脑血管病之间的相互关系做一综述。

关键词: 缺血性脑血管病, 内皮型一氧化氮合酶, 一氧化氮, 基因多态性, 内皮祖细胞, 综述

Abstract: Endothelial nitric oxide synthase (eNOS) and nitric oxide (NO) can adjust the recovery of blood flow after cerebral ischemia, inhibit inflammatory reaction and promote the regeneration of the nerve and blood vessels. The gene polymorphism of eNOS is closely related to the onset of ischemic cerebrovascular disease. This article reviewed the relationship between eNOS and ischemic cerebrovascular disease.

Key words: ischemic cerebrovascular disease, endothelial nitric oxide synthase, nitric oxide, gene polymorphism, endothelial progenitor cell, review