《中国康复理论与实践》

《中国康复理论与实践》 ›› 2015, Vol. 21 ›› Issue (02): 192-195.

• 临床研究 • 上一篇    下一篇

电针对脑卒中后抑郁患者脑血流量的影响

李厥宝，叶祥明，程瑞动，朱根应，杨婷   

  1. 浙江省人民医院康复医学科，浙江杭州市310014。
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2015-02-25 发布日期:2015-02-25

Effect of Electroacupuncture on Regional Cerebral Blood Flow in Patients with Post-stroke Depression

LI Jue-bao, YE Xiang-ming, CHENG Rui-dong, ZHU Gen-ying, YANG Ting   

  1. Department of Rehabilitation, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang 310014, China
  • Received:1900-01-01 Revised:1900-01-01 Published:2015-02-25 Online:2015-02-25

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被引次数

20

摘要： 目的研究电针对脑卒中后抑郁(PSD)患者局部脑血流量(rCBF)的影响。方法将21 例脑卒中后抑郁患者随机分为电针组(n=11)和药物组(n=10)。电针组取双侧合谷、太冲穴，每天1 次；药物组口服盐酸氟西汀分散片20 mg，每天1 次，均连续治疗8 周。患者分别于治疗前及治疗后2、4、8 周使用汉密尔顿抑郁量表(HAMD)进行评定，治疗前及治疗后8 周采用单光子发射计算机断层成像(SPECT)观察rCBF的变化。结果电针组治疗后2 周时HAMD低于药物组(P<0.05)，而治疗后4 周、8 周时无显著性差异(P>0.05)。治疗8 周后，电针组rCBF较药物组改善更佳(P<0.05)。结论电针治疗脑卒中后抑郁疗效明确，可能与改善卒中后脑灌注有关。

关键词: 脑卒中后抑郁, 电针, 脑局部血流量, 单光子发射计算机断层成像

Abstract: Objective To explore the therapeutic effects of electroacupuncture on regional cerebral blood flow (rCBF) in patients with post-stroke depression. Methods 21 patients with post-stroke depression were randomly divided into electroacupuncture group (n=11) and drug group (n=10). The electroacupuncture group received electroacupuncture on double Hegu (LI4) and Taichong (LR3) once a day for 8 weeks, while the drug group took fluoxetine hydrochloride dispersible tablets 20 mg a day for 8 weeks. They were evaluated with Hamilton Self-rating Scale for Depression (HAMD) before, and 2 weeks, 4 weeks and 8 weeks after treatment respectively. The rCBF were measured with single positron emission computerized tomography (SPECT) before and 8 weeks after treatment. Results The score of HAMD decreased more in the electroacupuncture group than in the drug group 2 weeks after treatment (P<0.05), and there was no significant difference between the two groups 4 and 8 weeks after treatment (P>0.05). The rCBF was significantly greater in the electroacupuncture group than in the drug group. Conclusion That electroacupuncture is effective on post-stroke depression, which may be related with the increase of the rCBF levels.

Key words: post-stroke depression, electroacupuncture, regional cerebral blood flow, single photon emission computed tomography