《中国康复理论与实践》

《中国康复理论与实践》 ›› 2014, Vol. 20 ›› Issue (8): 776-779.

• 临床研究 • 上一篇    下一篇

运动终板药物注射治疗痉挛型脑性瘫痪的效果

翟红印1,2，许予明2，谢晓明1
   

  1. 1.郑州大学第三附属医院脑瘫康复科，河南郑州市450052；2.郑州大学第一附属医院神经内科，河南郑州市450001
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2014-08-25 发布日期:2014-08-25

Effect of Drug Injection in Muscle Motor Points on Spastic Cerebral Palsy

ZHAI Hong-yin, XU Yu-ming, XIE Xiao-ming.
  

  1. Rehabilitation and Treatment Centre for Cerebral Palsy, the Third Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China
  • Received:1900-01-01 Revised:1900-01-01 Published:2014-08-25 Online:2014-08-25

PDF (PC)

摘要： 目的观察运动终板药物注射治疗痉挛型脑瘫患儿的效果。方法230 例痉挛型脑瘫患儿分为对照组和观察组，每组115 例。对照组给予综合康复，包括功能训练、物理因子治疗及药物应用；观察组在此基础上加痉挛肌肉运动终板注射维生素B1和维生素B12。治疗前后采用粗大运动功能测试(GMFM)评价患儿功能区的运动功能，采用改良Ashworth 量表(MAS)评价痉挛程度，采用CDCC婴幼儿智能发育量表测定智力发育指数(MDI)和心理运动发育指数(PDI)。结果治疗后，两组患儿的粗大运动功能明显改善，MAS分级明显降低，MDI和PDI评分明显增加(P<0.01)；且观察组均优于对照组(P<0.05)。结论肌肉运动终板药物注射能提高脑瘫患儿粗大运动功能，减轻痉挛，改善智力发育。

关键词: 脑性瘫痪, 痉挛, 运动终板, 药物注射, 维生素B1, 维生素B12

Abstract: Objective To explore the effect of drug injection in muscle motor points on children with spastic cerebral palsy. Methods 230 children with spastic cerebral palsy were divided into control group and observation group, with 115 cases in each group. The control group received comprehensive rehabilitation including functional training, physical therapy and medicine, while the observation group received injection of vitamin B1 and vitamin B12 in muscle motor points in addition. They were assessed with Gross Motor Function Measure (GMFM), modified Ashworth Scale (MAS), mental development index (MDI) and psychomoter developmental index (PDI) of CDCC Infant Me Ntal Development Scale. Results The gross motor function improved, MAS score decreased, the scores of MDI and PDI increased after treatment (P<0.01) in both groups, which were better in the observation group than in the control group (P<0.05). Conclusion Drug injection in muscle motor points can improve the gross motor function, relieve spasm, and improve intelligence development of children with spastic cerebral palsy.

Key words: cerebral palsy, spasm, motor end plate, drug injection, Vitamin B1, Vitamin B12