《中国康复理论与实践》

《中国康复理论与实践》 ›› 2002, Vol. 8 ›› Issue (09): 542-544.

• 临床康复 • 上一篇    下一篇

脑卒中后抑郁治疗的初步探索

杨明明   

  1. 北京博爱医院心理科 北京市 100077
  • 收稿日期:2002-07-19 出版日期:2002-09-25 发布日期:2002-09-25

Primary study of the effect of psychological treatment on patients with post-stroke depression

YANG Ming-ming   

  1. Department of Psychology,Beijing CharityHospital affiliated to China Rehabilitation Research Center,Beijing 100077,China.
  • Received:2002-07-19 Published:2002-09-25 Online:2002-09-25

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被引次数

41

摘要： 目的探索脑卒中后抑郁治疗的最佳方案。方法对1996—2001年间住院脑卒中患者在入院时进行自评抑郁量表(SDS)、自评焦虑量表(SAS)、老年认知功能量表(SECF)和日常生活能力量表(ADL)的检测并进行心理治疗。自评抑郁量表SDS≥50分为脑卒中后抑郁,符合入组条件的有115例,随机分为两组:心理治疗加上百忧解药物联合治疗组(甲组)54人,单用心理治疗组(乙组)61人。2个月后复查1次。结果两组在年龄、性别、受教育年限、病程和偏瘫左右侧方面无显著性差异。住院2个月后复查,两组抑郁、焦虑情绪明显降低(P<0.001),日常生活能力明显提高(P<0.001),认知功能改变不明显(P>0.5)。两组SDS、SAS、SECF、ADL两次测验降低或提高的分数无显著差异(P>0.5)。结论脑卒中后抑郁单用心理治疗与心理加上百忧解药物联合治疗疗效相似。

关键词: 脑卒中, 抑郁, 心理治疗, 百忧解, 药物治疗

Abstract: ObjectiveTo compare the effect of psychological treatment only and psychological combined with fluoxetine treatment in reducing symptom of depression, anxiety and in improving of cognitive and daily living abilities for post-stroke depression patients.MethodsAll patients with post-stroke enrolled in hospital between 1996 and 2001 and were evaluated by using of the Self-rating Depression Scale (SDS), the Self-rating Anxiety Scale (SAS), Scale of Elderly Cognitive Function (SECF), and Ability of Daily Living (ADL). SDS score was equal or greater than 50 points (SDS≥50) selected as subjects for this study. A total of 115 patients were randomized divided into psychological with fluoxetine treatment group (Group A,54 patients) and psychological treatment group (Group B,61 patients). There is no significant difference between two groups in age, education, and left or right side of hemiplegics. Statistical analysis was performed by using Chi test and t test to compare the 2 groups at day 0 (baseline) and after 2 months.ResultsThe level of depression and anxiety reduced significantly in both Group A and Group B from baseline to end of treatment (P<0.001). Both groups had significant improvement in daily living ability (P<0.001).There was no significant improvement in cognitive ability (P>0.5). There was no significant differences on SDS, SAS, SECF, and ADL scores from baseline to end of treatment (P>0.5).Conclusions There were similar effect of psychological with fluoxetine treatment and of psychological treatment only on post-stroke depression.

Key words: stroke, depression, psychological treatment, fluoxetine, medical treatment