《中国康复理论与实践》

《中国康复理论与实践》 ›› 2014, Vol. 20 ›› Issue (5): 446-450.

• 论文 • 上一篇    下一篇

MicroRNAs与动脉粥样硬化

曹幸毅，袁明，夏东晖，吴士文   

  1. 1.中国人民武装警察部队总医院神经内科，北京市100039；2.中国航天员科研训练中心，北京市100094。
  • 收稿日期:2013-10-19 修回日期:2013-11-20 出版日期:2014-05-25 发布日期:2014-05-25
  • 通讯作者: 吴士文

MicroRNAs and Atherosclerosis (review)

CAO Xing-yi, YUAN Ming, XIA Dong-hui, et al.   

  1. Department of Neurology, Chinese People's Army Police Force General Hospital, Beijing 100039, China
  • Received:2013-10-19 Revised:2013-11-20 Published:2014-05-25 Online:2014-05-25

PDF (PC)

被引次数

1

摘要： 哺乳动物细胞内microRNAs (miRNAs)的发现使对疾病研究的重点转向转录后调节机制方面。在心血管系统中发现多种miRNAs与动脉粥样硬化病的发生发展密切相关。本文从动脉粥样硬化各大学说板块的角度，综述miRNAs在动脉粥样硬化发病机制中的作用和进展。

关键词: microRNA, 动脉粥样硬化, 血管内皮细胞, 炎症, 综述

Abstract: The discovery of microRNAs (miRNAs) in mammalian cells has renewed the focus on posttranscriptional regulatory mechanisms during pathogenesis. The studies have showed that miRNAs play a key role in atherosclerosis development and progress, and were reviewed in this paper.

Key words: microRNA, atherosclerosis, vascular endothelial cell, inflammation, review