《中国康复理论与实践》

《中国康复理论与实践》 ›› 2013, Vol. 19 ›› Issue (09): 887-889.

• 论文 • 上一篇    下一篇

非运动症状对帕金森病患者生活质量的影响

黄星会，霍丽涛，梁伟，吴庆文，崔颖，孙维，罗贻春   

  1. 1.河北联合大学护理与康复学院，河北唐山市063000；2.河北联合大学临床医学院，河北唐山市063000；3.河北省唐山市脑血管病医院，河北唐山市063000；4.江苏省扬州市第二人民医院，江苏扬州市225007。
  • 收稿日期:2012-10-14 修回日期:2012-11-28 出版日期:2013-09-25 发布日期:2013-09-25
  • 通讯作者: 吴庆文

Non-motor Symptoms of Parkinson's disease Associated with Quality of Life

HUANG Xing-hui, HUO Li-tao, LIANG Wei, et al.   

  1. College of Nursing and Rehabilitation, Hebei United University, Tangshan 063000, Hebei, China
  • Received:2012-10-14 Revised:2012-11-28 Published:2013-09-25 Online:2013-09-25

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摘要： 目的研究帕金森病患者非运动症状(NMS)的分布及其对生活质量的影响。方法对50 例帕金森病患者及50 名正常人分别用NMS 问卷和健康调查简表(SF-36)进行调查，并行Spearman 相关分析。结果帕金森病患者98%伴有NMS，以近记忆力下降、便秘、不宁腿发生率最高；与正常人比较，除性欲改变、性生活困难和恶心或呕吐3 项外，均有显著性差异(P<0.05)。SF-36 的8 个维度两组比较均有显著性差异(P<0.05)。便秘、近记忆力下降、注意力下降、不宁腿和睡眠障碍与SF-36 评分相关(P<0.05)。结论帕金森病患者中NMS 的发生率很高，并对生活质量有很大影响。

关键词: 帕金森病, 非运动症状, 生活质量

Abstract: Objective To investigate the status about non-motor symptoms (NMS) in Parkinson's disease (PD) patients and the effect on quality of life. Methods 50 PD patients and 50 normal controls were investigated with the NMS questionnaire and the Healthy Survey short form (SF-36), and analysed with Spearman correlation. Results 98% of PD patients presented NMS, and recent memory loss, restless legs,constipation were the most frequent. All the NMS were more frequent than in the controls (P<0.05) except sexual desire, sexual difficulties and nausea or vomiting. All the dimensions of SF-36 were significantly different between the groups (P<0.05). The symptoms of constipation,decline in recent memory, decreased attention, restless legs and sleep disorders correlated with the scores of SF-36 (P<0.05). Conclusion NMS is common in PD patients, and impacts their quality of life.

Key words: Parkinson's disease, non-motor symptoms, quality of life