《中国康复理论与实践》

《中国康复理论与实践》 ›› 2013, Vol. 19 ›› Issue (2): 180-182.

• 论文 • 上一篇    下一篇

难治性癫痫术前间期脑电图与术后癫痫发作结局的关系：168 例病例分析

赵媛，黄上萌，丁成赟   

  1. 1.北京市顺义区医院神经内科，北京市101306；2.厦门大学附属第一医院，福建厦门市361003；3.解放军总医院第一附属医院(解放军第304 医院)神经内科， 北京市100037。
  • 收稿日期:2012-02-10 修回日期:2012-09-15 出版日期:2013-02-25 发布日期:2013-02-25
  • 通讯作者: 丁成赟

Relationship between Electroencephalogram in Preoperative Evaluation and Postoperative Seizures Ending: 168 Cases Report

ZHAO Yuan, HUANG Shang-meng, DING Cheng-yun   

  1. Beijing Shunyi Hospital, Beijing 101306, China
  • Received:2012-02-10 Revised:2012-09-15 Published:2013-02-25 Online:2013-02-25

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摘要： 目的回顾性总结临床难治性癫痫患者发作间期脑电图特点并分析间期脑电图的特点与术后早、中期癫痫发作结局的关系。方法回顾168 例经北京天坛医院癫痫中心严格术前评估并实施手术治疗的难治性癫痫患者发作间期的脑电图特点，随访术后2 年和5 年的癫痫发作结局，分析发作间期脑电图与手术后不同时期癫痫发作结局的关系。结果73 例难治性癫痫患者术后2年和术后5 年癫痫发作结局间的差异无统计学意义(χ2=5.07, P>0.05)；单侧异常放电与双侧异常放电在术后发作结局间的差异有统计学意义(χ2=15.58, P<0.05)。结论难治性癫痫发作间期异常放电局限于一侧大脑半球，且主要局限于颞叶者术后2 年的癫痫发作，结局改善较好。

关键词: 难治性癫痫, 间期脑电图, 癫痫发作结局

Abstract: Objective To retrospectively conclude the characteristics of interictal EEG of patients with intractable epilepsy, and then analyze their relationship with postoperative seizures. Methods 168 patients with intractable epilepsy in the epilepsy center of Beijing Tiantan Hospital that underwent strictly preoperative evaluations before surgery were collected and followed up for 2 and 5 years, the characteristics of their interictal EEG and postoperative seizures after 2 years and 5 years were concluded and analyzed. Results There was no significant difference between 2 years and 5 years postoperative seizures in 73 intractable epilepsy patients (P>0.05). There was statistically differences in postoperative seizures between unilateral and bilateral abnormal discharges (P<0.05). Conclusion Patients with unilateral abnormal discharges and located at temporal in interictal EEG predict better outcomes 2 years after operation.

Key words: intractable epilepsy, interictal electroencephalogram, postoperative seizures