《中国康复理论与实践》

《中国康复理论与实践》 ›› 2012, Vol. 18 ›› Issue (11): 1069-1070.

• 论文 • 上一篇    下一篇

脑白质疏松危险因素的回归分析

张爱娟1，王素珍2a，王金红2b   

  1. 1.潍坊市脑科医院神经内科，山东潍坊市261021；2.潍坊医学院，a.统计学教研室；b.药理教研室，山东潍坊市261053。
  • 收稿日期:2012-05-13 修回日期:2012-06-25 出版日期:2012-11-25 发布日期:2012-11-25

Risk Factors for Leukoaraiosis: A Logistic Regression Analysis

ZHANG Ai-juan, WANG Su-zhen, WANG Jin-hong.   

  1. Department of Neurology,Brain Hospital of Weifang, Weifang 261021, Shandong, China
  • Received:2012-05-13 Revised:2012-06-25 Published:2012-11-25 Online:2012-11-25

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摘要： 目的探讨脑白质病变的危险因素。方法以脑血管病入院的患者204 例，以白质病变等级为因变量，可能的影响因素为自变量，采用SAS 9.2 软件进行非条件Logistic 回归分析。显著性水平α=0.10。结果共有5 个因素纳入回归方程：有无狭窄、年龄、低密度脂蛋白、载脂蛋白B 和载脂蛋白A，前4 项为危险因素(OR>1, P<0.05)，载脂蛋白A 为保护因素(OR=0.715, P=0.0993)。结论动脉粥样硬化的危险因素同样为脑白质病变的危险因素；脑白质病变与颈部大血管狭窄密切相关。

关键词: 脑白质疏松, 动脉粥样硬化, 颈动脉狭窄, 回归分析

Abstract: Objective To investigate the risk factors for leukoaraiosis. Methods 204 cases of inpatients were registered. The severity of leukoaraiosis was as the dependent variable, the possible risk factors were as independent variables, unconditional logistic regression was analyzed with SAS 9.2 software, significant level α=0.10. Results 5 factors, that were carotid stenosis, age, low density lipoprotein cholesterol,apolipoprotein B and apolipoprotein A, were included, in which the former 4 were risk factors (OR>1, P<0.05), the latter was protection factor (OR=0.715, P=0.0993). Conclusion The vascular risk factors contribute to formation of leukoaraiosis, and carotid stenosis relate to leukoaraiosis.

Key words: leukoaraiosis, atherosclerosis, carotid stenosis, regression analysis