《中国康复理论与实践》

《中国康复理论与实践》 ›› 2012, Vol. 18 ›› Issue (10): 919-921.

• 论文 • 上一篇    下一篇

苯海索在小儿脑性瘫痪肌张力障碍治疗中的应用

杨雪，曹建国   

  1. 深圳市儿童医院康复科，广东深圳市518026
  • 收稿日期:2012-04-17 修回日期:2012-05-30 出版日期:2012-10-25 发布日期:2012-10-25
  • 通讯作者: 曹建国

Application of Trihexyphenidyl in Dystonia in Children with Cerebral Palsy (review)

YANG Xue, CAO Jian-guo   

  1. Department of Rehabilitation Medicine, Shenzhen Children's Hospital, Shenzhen 518026, Guangdong, China
  • Received:2012-04-17 Revised:2012-05-30 Published:2012-10-25 Online:2012-10-25

PDF (PC)

摘要： 肌张力障碍是脑瘫患儿常见的临床表现，它可致运动功能障碍、言语功能障碍、吞咽困难及流涎。苯海索(安坦)是一种中枢性抗胆碱药，它用于治疗成人肌张力障碍的历史悠久，但治疗小儿脑瘫肌张力障碍的临床经验相对较少。本文就苯海索治疗小儿脑瘫肌张力障碍的疗效、用法用量、不良反应及作用机制进行综述。

关键词: 肌张力障碍, 脑性瘫痪, 苯海索, 综述

Abstract: Dystonia is common in children with cerebral palsy. It can cause motor dysfunction, and is frequently associated with altered speech articulation, abnormal swallowing, and excessive drooling. Although trihexyphenidyl (Artane) is an anticholinergic agent with a long history of use in the management of dystonia in adults, information is limited regarding the use of trihexyphenidyl in children. This study reviewed the clinical experience of the use of trihexyphenidyl in children with cerebral palsy for dystonia, with special emphasis on benefits and tolerability.

Key words: dystonia, cerebral palsy, trihexyphenidyl, review