《中国康复理论与实践》

《中国康复理论与实践》 ›› 2012, Vol. 18 ›› Issue (6): 577-578.

• 论文 • 上一篇    下一篇

高龄不稳定性心绞痛患者血清胱抑素水平对近期预后的影响

李铁岭，鲁晓春，彭卫红，范利   

  1. 解放军总医院干部诊疗科，北京市100853。
  • 收稿日期:2011-10-24 修回日期:2012-01-18 出版日期:2012-06-25 发布日期:2012-06-25
  • 通讯作者: 范利

Impact of Serum Cystatin C Level on Short Term Prognosis in Elderly Patients with Unstable Angina

LI Tie-ling, LU Xiao-chun,PENG Wei-hong, et al.   

  1. Chinese PLA General Hospital, Beijing 100853, China
  • Received:2011-10-24 Revised:2012-01-18 Published:2012-06-25 Online:2012-06-25

PDF (PC)

被引次数

8

摘要：

目的探讨血清胱抑素C(Cys C)水平与不稳定心绞痛患者近期预后的关系。方法采用散色免疫比浊法测定167 例不稳定心绞痛患者血清Cys C 浓度等指标，观察患者24 h 内首次血清Cys C 值，<1.5 mg/L 者入正常组(102 例)，≥1.5 mg/L 者入高Cys C 组(65 例)。记录住院期间及出院6 个月内主要心血管事件、病死率和再入院率。结果高Cys C 组患者心血管事件、病死率和再入院率等终点事件高于正常组(χ2=4.16, P=0.042)。结论血清Cys C水平与不稳定性心绞痛患者近期预后有密切的关系，血清CysC可作为不稳定性心绞痛患者近期心血管事件的预测因子。

关键词: 不稳定性心绞痛, 胱抑素C, 脑钠肽, 预后

Abstract: Objective To evaluate the impact of serum cystatin C (Cys C) level on short term prognosis in elderly patients with unstableangina (UA). Methods 167 patients with US were involved in this study. The serum Cys C level was measured by immunonephelometric assay.The patients were divided into normal group (Cys C<1.5 mg/L, n=102) and high Cys C group (Cys C≥1.5 mg/L, n=65) according totheir baseline of the first Cys C level within 24 hours. The clinical outcomes, including major cardiac events, mortality and readmission duringhospitalization and 6 months in the follow-up period were observed and evaluated. Results The major cardiac events, mortality and readmissionrate were higher in the high Cys C group than in the normal group (χ2=4.16, P=0.042). Conclusion The serum of Cys C level isclosely related to the short term prognosis of UA, it could be a risk factor to predict major cardiac events in patients with UA.

Key words: unstable angina, cystatin C, brain natriuretic peptide, prognosis