《中国康复理论与实践》

《中国康复理论与实践》 ›› 2012, Vol. 18 ›› Issue (3): 247-249.

• 论文 • 上一篇    下一篇

N-甲基-D-天门冬氨酸受体、脑缺血性损伤和运动训练

张安静1，白玉龙1,2   

  1. 1.复旦大学附属华山医院康复医学科，上海市 200040；2.复旦大学附属华山医院永和分院康复医学科，上海市 200436。
  • 收稿日期:2011-11-22 修回日期:1900-01-01 出版日期:2012-03-25 发布日期:2012-03-25

N-methyl-D-aspartate Receptor, Cerebral Ischemia and Exercise (review)

ZHANG An-jing, BAI Yu-long.   

  1. Department of Rehabilitation Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China
  • Received:2011-11-22 Revised:1900-01-01 Published:2012-03-25 Online:2012-03-25

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摘要： N-甲基-D-天门冬氨酸(NMDA)受体是一种离子型谷氨酸受体，与突触可塑性、皮质和海马神经元长时程增强和抑制效应等中枢神经系统的生理、病理过程相关。本文就近年来NMDA受体在脑缺血中所起作用的研究进展进行综述。

关键词: N-甲基-D-天门冬氨酸受体, 脑缺血, 运动, 综述

Abstract: N-methyl-D-aspartate (NMDA) receptors are a group of ionotropic glutamate receptors, which are in close contact with the synaptic plasticity, long-term potentiation (LTP) and long-term depression (LTD) in the cerebral cortex or the hippocampus. This article reviewed the recent development in this field.

Key words: N-methyl-D-aspartate receptor, cerebral ischemia, exercise, review