《中国康复理论与实践》

《中国康复理论与实践》 ›› 2012, Vol. 18 ›› Issue (2): 165-168.

• 论文 • 上一篇    下一篇

雌激素保护期成年截瘫女性血脂代谢研究

雒生杰，李建军，周红俊   

  1. 1.首都医科大学康复医学院，北京市 100068；2.中国康复研究中心北京博爱医院，北京市 100068。
  • 收稿日期:2011-04-14 修回日期:2011-05-26 出版日期:2012-02-25 发布日期:2012-02-25
  • 通讯作者: 李建军

Serum Lipid Profile in Chinese Premenopausal Women with Chronic Paraplegia

LUO Sheng-jie, LI Jian-jun, ZHOU Hong-jun.   

  1. Beijing Charity Hospital, China Rehabilitation Research Centre, Capital Medical University School of Rehabilitation Medicine, Beijing 100068, China
  • Received:2011-04-14 Revised:2011-05-26 Published:2012-02-25 Online:2012-02-25

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被引次数

4

摘要： 目的通过流行病学调查了解绝经前截瘫女性血脂水平，探讨截瘫致缺乏运动对雌激素保护期女性血脂代谢的影响。方法2004~2009 年中国康复研究中心截瘫女性住院患者183 例入院时行血脂状态调查。血脂观察指标：甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白(LDL)和高密度脂蛋白(HDL)。结果截瘫女性TG、TC 水平显著高于女性全国平均水平，分别达到1.44mmol/L 和4.45 mmol/L；HDL、LDL 平均水平均与女性全国平均水平无显著性差异。年龄与TG(r=0.158, P<0.05)、TC(r=0.271, P<0.01)、LDL(r=0.207, P<0.01)呈正相关；与HDL 无显著性相关。总体血脂异常发生率60%，依次为低HDL(33%)、高TC(25%)、高TG(24%)、高LDL(21%)。结论在雌激素保护作用下，HDL 代谢受缺乏运动的影响较小，但TG、TC代谢仍有一定程度紊乱，心血管疾病风险增加。

关键词: 女性, 雌激素保护, 截瘫, 缺乏运动, 血脂

Abstract: Objective To investigate the characteristics of serum lipids levels in young women with paraplegia in sedantary lifestyles.Methods 183 female paraplegics who admitted in China Rehabilitation Research Centre (CRRC) from Jan 2004 to Dec 2009 were investigated.Lipid profiles included triglyceride (TG), total cholesterol (TC), low density lipoprotein (LDL), and high-density lipoprotein (HDL).Results Female paraplegics showed higher mean TG and TC levels than mean levels of Chinese females (TG 1.44 mmol/L vs. 1.24 mmol/L; TC 4.45 mmol/L vs. 4.30 mmol/L). But no difference was found in HDL and LDL levels. TG, TC and LDL levels were correlated positively to age (r=0.158, P<0.05; r=0.271, P<0.01; r=0.207, P<0.01, respectively), but HDL showed no correlation to age. Prevalence of dislipidemia was 60%, including low HDL(33%), high TC(25%), high TG(24%), and high LDL(21%). Conclusion Lack of exercise may result in some dyslipidemia and increase cardiovascular risks in women who are under estrogen protection.

Key words: female, estrogen protection, paraplegia, lack of exercise, lipid