《中国康复理论与实践》

《中国康复理论与实践》 ›› 2010, Vol. 16 ›› Issue (5): 417-418.

• 论文 • 上一篇    下一篇

经皮冠状动脉介入术后患者血小板抑制率的血栓弹力图测定

布伦，唐发宽，齐帜，华宁，陆宏   

  1. 解放军第309医院心内科，北京市 100091。
  • 收稿日期:2009-11-09 修回日期:2010-01-25 出版日期:2010-05-25 发布日期:2010-05-25
  • 通讯作者: 唐发宽

Platelet Inhibition Ratio by Thromboelastography in Patients Undergoing Percutaneous Coronary Intervention

BU Lun, TANG Fa-kuan, QI Zhi, et al.   

  1. Department of Cardiology, 309th Hospital, Beijing 100091, China
  • Received:2009-11-09 Revised:2010-01-25 Published:2010-05-25 Online:2010-05-25

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被引次数

24

摘要： 目的探讨经皮冠状动脉介入治疗（PCI）的患者中，使用血栓弹力图（TEG）所测定的血小板抑制率的变化及临床意义。方法根据6个月内有无再发缺血事件,将入选的118例PCI患者分为缺血事件组22例与非缺血事件组96例，计算两组患者经TEG测定的血小板抑制率。结果缺血事件组与非缺血事件组患者相比较，二磷酸腺苷诱导的血小板抑制率明显降低(P<0.01)，而花生四烯酸诱导的血小板抑制率无显著性差异(P＞0.05)。结论冠心病患者PCI术后缺血事件的发生，可能与对氯吡格雷的抵抗有关。

关键词: 经皮冠状动脉介入治疗, 血栓弹力图, 血小板抑制率

Abstract: ObjectiveTo investigate the platelet inhibition ratio by thromboelastography (TEG) and its clinical impact in patients undergoing percutaneous coronary intervention (PCI). Methods118 PCI patients were divided into ischemic events group (22 cases) and nonischemic events group (96 cases) according to their clinical follow-up of 6 months. Platelet inhibition ratio was measured by TEG. ResultsADP-induced platelet inhibition ratio of ischemic events group decreased significantly compared with nonischemic events group (P<0.01). And there were no significant differences in AA-induced platelet inhibition ratio between two groups (P＞0.05). ConclusionThere may be some relationship between the ischemic events of PCI patients and their drug resistance to clopidogrel.

Key words: percutaneous coronary intervention, thromboelastography, platelet inhibition ratio