《中国康复理论与实践》

《中国康复理论与实践》 ›› 2010, Vol. 16 ›› Issue (3): 253-256.

• 论文 • 上一篇    下一篇

母语为汉语中国人语言区的皮质电刺激研究

张亚清1a，张忠1b，张玉梅1a，江涛1b   

  1. 1.首都医科大学附属北京天坛医院，a.神经内科;b.神经外科,北京市 100050。
  • 收稿日期:2009-10-12 修回日期:2010-02-23 出版日期:2010-03-25 发布日期:2010-03-25
  • 通讯作者: 张忠

Study of Language Cortex Organization Characteristics of Native Chinese by Intraoperative Cortical Electrical Stimulation

ZHANG Ya-qing, ZHANG Zhong, ZHANG Yu-mei, et al.   

  1. Department of Neurology, Capital Medical University Tiantan Hospital, Beijing 100050, China
  • Received:2009-10-12 Revised:2010-02-23 Published:2010-03-25 Online:2010-03-25

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摘要： 目的研究母语为汉语中国人语言区的构筑特点。方法回顾性分析手术治疗20例优势半球语言区低级别胶质瘤。在唤醒麻醉下应用术中皮质电刺激确定语言区。结果16例患者至少发现1个以上语言阳性部位，3例患者仅额叶有语言阳性部位，1例患者仅颞叶有语言阳性部位。语言阳性部位主要分布在侧裂周围，额下回语言阳性部位基本符合经典的Broca区；颞上回语言阳性部位明显多于颞中回。结论个体之间语言阳性部位的分布存在较大变异，经典的语言-解剖模式需要改进。由于患者例数太少，目前的数据尚不能完全反映母语为汉语中国人语言区的构筑特点。

关键词: 语言皮质, 汉语, 脑定位, 皮质电刺激

Abstract: ObjectiveTo investigate the language cortex organization characteristics of native Chinese. Methods20 patients who underwent language mapping via intraoperative direct cortical electrical stimulation (ioDCES) under awake anaesthesia for glioma in dominant hemisphere were analyzed retrospectively. Results16 patients were identified at least one language site, 3 patients located in the frontal and 1 patient in the temporal lobe. The language sites mostly located in the perisylvian region. The frontal language sites conformed to traditional Broca's areas, but the superior temporal gyrus contained much more language sites than the middle temporal gyrus.ConclusionHigh individual variability in language organization indicates a need for revision of the classical model of language localization. Because of the samples were too small, our current dates can't fully reflect language cortex organization characteristics of native Chinese.

Key words: language cortex, Chinese, brain mapping, cortical electrical stimulation