《中国康复理论与实践》

《中国康复理论与实践》 ›› 2006, Vol. 12 ›› Issue (08): 687-688.

• 基础研究 • 上一篇    下一篇

电针至阳穴对急性心肌缺血家兔血浆cAMP、cGMP含量的影响

刘宝华; 金佳佳; 周筱春; 李勇   

  1. 温州医学院附属二院,浙江温州市 325027
  • 收稿日期:2005-08-15 出版日期:2006-08-01 发布日期:2006-08-01

Effect of Stimulating “Zhiyang” (DU 9) with Electric Acupuncture Apparatus on Contents of cAMP and cGMP in Plasma of Experimental Acute Myocardial Ischemic Rabbits

LIUBao-hua, JIN Jia-jia, ZHOUXiao-chun, et al   

  1. The Second Affiliated Hospital of Wenzhou Medical College, Wenzhou 325027, Zhejiang, China
  • Received:2005-08-15 Published:2006-08-01 Online:2006-08-01

PDF (PC)

被引次数

31

摘要： 目的观察电针至阳穴对急性心肌缺血家兔血浆环磷酸腺苷(cAMP)、环磷酸鸟苷(cGMP)含量的影响。方法40只家兔随机分为4组:正常对照组(A组)、单纯造模组(B组)、造模+电针内关穴组(C组)、造模+电针至阳穴组(D组),采用垂体后叶素(2U/kg)造成家兔心肌急性缺血,在全过程中多次测定Ⅱ导联心电图,并用放射免疫法测定电针后家兔血浆cAMP、cGMP含量。结果C组和D组家兔血浆中cAMP含量明显低于B组(P<0.01),与A组比较无显著性差异(P>0.05),C组与D组间亦无显著性差异(P>0.05);各组间cGMP含量无显著性差异(P>0.05)。结论电针至阳穴可提高家兔心肌对缺血缺氧的耐受力,改善心肌的缺血缺氧状态,与电针内关穴有同等效果。

关键词: 至阳穴, 急性心肌缺血, 心电图, 环磷酸腺苷(cAMP), 环磷酸鸟苷(cGMP)

Abstract: ObjectiveTo observe the effect of stimulating “Zhiyang” (DU 9) with electric acupuncture apparatus on contents of cAMP and cGMP in plasma of experimental acute myocardial ischemic rabbits.Methods40 rabbits were randomly divided into four groups: the normal control group (A), model group (B), model plus electric acupuncture on “Neiguan” (P 6) group (C) and model plus electric acupuncture on DU 9 group (D). The acute myocardial ischemic model was established by pituitrin (2 U/kg) injected into the vein of rabbit. Electrocardiogram (ECG) of Ⅱ leads was observed and contents of cAMP and cGMP in plasma were tested after electric acupuncture by radio immunoassay.ResultsThe cAMP contents of the group C and group D were lower than that of the group B significantly ( P<0.01), but not different from that of the group A ( P>0.05), and there was no difference between the group C and group D. The contents of cGMP were not different among four groups ( P>0.05).ConclusionPuncturing DU 9 can raise the myocardial endurance to the insufficiency of blood and oxygen. The effects of electric acupuncture on DU 9 and P 6 are the same.

Key words: Zhiyang (DU 9), acute myocardial ischemia, electrocardiogram, cAMP, cGMP