《中国康复理论与实践》

《中国康复理论与实践》 ›› 2006, Vol. 12 ›› Issue (08): 663-664.

• 专题 脑损伤及其并发症 • 上一篇    下一篇

大面积脑梗死并高热老年患者的亚低温治疗疗效观察

卢红玉; 庞全瑭; 刘淑萍   

  1. 荣成市人民医院神经内科,山东荣成市 264300
  • 收稿日期:2006-01-09 出版日期:2006-08-01 发布日期:2006-08-01

Effect of Mild Hypothermia Therapy on Elderly Patients with Massive Hemispheric Infarction and Hyperpyrexia

LU Hong-yu, PANG Quan-tang, LIU Shu-pin   

  1. The Department of Neurology, Rongcheng People's Hospital, Rongcheng 264300, Shandong, China
  • Received:2006-01-09 Published:2006-08-01 Online:2006-08-01

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摘要： 目的观察亚低温治疗对大面积脑梗死并高热老年患者生命体征的影响及其临床疗效。方法46例发病24h内入院的老年大面积脑梗死并高热患者随机分为亚低温组和对照组各23例。亚低温组给予33℃～35℃的低温治疗,对照组给予常规降温治疗,10d后评定两组患者的体温、心率等,并根据死亡率及神经功能缺损评分评估患者的预后。结果10d后,亚低温组患者的体温、心率均低于对照组,死亡率亦低于对照组,神经功能改善(P<0.05),预后较好。结论亚低温治疗老年大面积脑梗死并高热患者安全有效。

关键词: 脑梗死, 高热, 低温, 预后

Abstract: ObjectiveTo observe the effect of mild hypothermia on vital signs of the elderly patients with anterior circulation brain infarction (massive hemispheric infarction) and hyperpyrexia.Methods46 elderly patients with massive hemispheric infarction and hyperpyrexia within the first 24 hours after onset were randomly divided into the control group and the hypothermia group with 23 cases in each group. The patients of the hypothermia group were treated with mild hypothermia therapy (33℃～35℃). Those of the control group were treated with routine hypothermal treatment. The temperature and heart rate of all patients were measured after 10 days; the prognosis was evaluated according to mortality and scores of Neurological Deficit Scale (NDS).ResultsFor patients of the hypothermia group, the temperature and heart rate significantly reduced, death rate was significantly lower, the neurological function distinctly improved and prognosis was better than the control group after 10 days treatment ( P<0.05).Conclusion Mild hypothermia is safe and effective to elderly patients with massive hemispheric infarction and hyperpyrexia.

Key words: brain infarction, hyperpyrexia, hypothermia, prognosis