《中国康复理论与实践》

《中国康复理论与实践》 ›› 2006, Vol. 12 ›› Issue (07): 556-558.

• 专题 脊髓损伤康复 • 上一篇    下一篇

脊髓损伤后神经修复的研究进展

赵宁; 李林   

  1. 首都医科大学宣武医院药物研究室,教育部神经变性病学重点实验室,北京市 100053
  • 收稿日期:2006-04-30 出版日期:2006-07-01 发布日期:2006-07-01

Nerve Regeneration after Spinal Cord Injury(review)

ZHAO Ning,LI Li   

  1. Department of Pharmacology, Xuanwu Hospital,Capital University of Medical Science, Beijing 100053, China
  • Received:2006-04-30 Published:2006-07-01 Online:2006-07-01

PDF (PC)

被引次数

9

摘要： 传统观点认为,中枢神经系统损伤后受损神经元和轴突不能再生。近年来的研究发现,成年动物脊髓损伤后,可以有不同程度的恢复,在适当的生长环境下,中枢神经系统内的一些受损的神经元轴突能有少许再生,并能与靶细胞形成功能性的突触联系。应用神经营养因子、细胞移植治疗脊髓损伤的研究正在迅速发展中。

关键词: 脊髓损伤, 神经修复, 综述

Abstract: There was an early view that the injured neurons and axons in central neural system couldn't regenerate after injury. However, it was found by recent researches that the injured neurons and axons can recover in different degrees after spinal cord injury of adult animals. In proper environment, some injured axons of central nervous system can regenerate slightly and form functional synaptic connections with target cells. Based on that, application of neurotrophic factors and cellular transplant therapy might be developed to treat spinal cord injury in the future.

Key words: spinal cord injury, nerve regeneration, review