《中国康复理论与实践》

《中国康复理论与实践》 ›› 2007, Vol. 13 ›› Issue (11): 1068-1069.

• 临床研究 • 上一篇    下一篇

西酞普兰联合康复训练治疗脑卒中后抑郁疗效观察

朱其秀; 李媛; 刘淑芹; 王强; 孟萍萍   

  1. 青岛大学医学院附属医院康复医学科,山东青岛市 266003
  • 收稿日期:2007-05-08 出版日期:2007-11-01 发布日期:2007-11-01

Effects of Citalopram and Physical Therapy on Post-stroke Depression

ZHU Qi-xiu, LI Yuan, LIU Shu-qin, et al   

  1. Department of Rehabilitation Medicine, Affiliated Hospital of Qingdao Medical College, Qingdao University, Qingdao 266003, Shandong,China
  • Received:2007-05-08 Published:2007-11-01 Online:2007-11-01

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被引次数

9

摘要： 目的观察西酞普兰联合康复运动训练对脑卒中后抑郁患者的效果。方法将72例脑卒中后抑郁患者随机分为药物组和对照组。其中对照组36例采用综合康复训练方法,药物组36例在康复训练的基础上采用口服西酞普兰治疗。采用Zung抑郁自评量表(ZSDA)和改良的巴氏指数(MBI)对两组患者治疗前后的抑郁程度和日常生活活动能力(ADL)进行评定。结果治疗后,两组患者抑郁程度较治疗前均有明显降低(P<0.01),且药物组疗效优于对照组(P<0.05);两组患者生活自理能力较治疗前有明显提高(P<0.01),两组间比较无显著性差异(P>0.05)。结论西酞普兰联合康复训练对脑卒中后抑郁的改善有明显疗效。

关键词: 西酞普兰, 运动疗法, 康复, 脑卒中后抑郁

Abstract: Objective To observe the effects of citalopram and physical therapy on poststroke depression(PSD).Methods72 patients with PSD were randomly divided into medicine group(n=36)and control group(n=36).The patients in the control group were treated only with physical therapy and the patients in the medicine group were treated with Citalopram and physical therapy.All patients were assessed with Zung Self-Rating Depression Scale(ZSDS)and Modified Barthel index(MBI)before and after treatment.ResultsAfter treatment,the Zung score in both groups decreased significantly(P<0.01).Meanwhile,the medicine group showed significantly less depression than the control group(P<0.05).The score of MBI was also significantly increased after treatment(P<0.01)in both group,but there was no significant difference between two groups(P>0.05).ConclusionCitalopram combined with physical therapy is effective on PSD.

Key words: Citalopram, physical therapy, rehabilitation, poststroke depression