《中国康复理论与实践》

《中国康复理论与实践》 ›› 2007, Vol. 13 ›› Issue (10): 946-948.

• 综述 • 上一篇    下一篇

MRI对膝骨关节炎的早期诊断意义

李珩; 李峰; 张蓉; 王常海   

  1. 北京中医药大学基础医学院中医诊断系,北京市 100029
  • 收稿日期:2007-05-23 出版日期:2007-10-01 发布日期:2007-10-01

Significance of Magnetic Resonance Imaging for Early Diagnosis of Knee Ostarthritis(review)

LI Heng, LI Feng, ZHANG Rong, et al   

  1. The Department of Traditional Chinese Diagnostics, Schoolof Preclinical Medicine, Beijing University of Chinese Medicine,Beijing 100029, China
  • Received:2007-05-23 Published:2007-10-01 Online:2007-10-01

PDF (PC)

被引次数

27

摘要： 对膝骨关节炎的研究显示,在软骨发生形态学改变之前,已经存在蛋白多糖和水含量的变化及表层胶原纤维定向排列的改变。MRI作为一种多参数影像学检查方法,通过应用弥散加权成像、质子密度地图成像、延迟动态增强成像、23Na+谱成像、T2Mapping成像等新的成像技术,不仅可以精确显示关节软骨的病理变化,而且可以在软骨发生病理形态学改变之前及时发现其基质成分变化,从而对膝骨关节炎的软骨损害进行早期诊断。随着设备软硬件技术的不断提高,MRI将在膝骨关节炎的早期诊断和疗效量化评判方面有广泛的应用前景。

关键词: 膝骨关节炎, 软骨基质, 磁共振成像, 综述

Abstract: During the latest researches on knee ostarthritis,it is discovered that before the morphology changes of cartilage,there were changes of the content of proteoglycan and water and changes of alinement of surface layer collagen fibers in cartilage matrix.By the new technologies of DWI,proton density mapping image,23Na MRI,T2Mapping image and so on,not only the pathological changes of cartilage can be disclosed,the component changes of cartilage matrix can also be detected.Accompany with the progress in the technology of software and hardware,MRI will have more and more prospects in early diagnosis and therapeutic effect evaluation of knee ostarthritis.

Key words: knee ostarthritis, cartilage matrix, magnetic resonance imaging(MRI), review