《中国康复理论与实践》

《中国康复理论与实践》 ›› 2007, Vol. 13 ›› Issue (09): 893-894.

• 临床研究 • 上一篇    下一篇

老年男性2型糖尿病与血清睾酮的相关性分析

吴晓琰; 陈蔚   

  1. 复旦大学附属华山医院老年科,上海市 200040
  • 收稿日期:2007-05-31 出版日期:2007-09-01 发布日期:2007-09-01

Correlation between Serum Testosterone and Type 2 Diabetes Mellitus in Elderly Male

WU Xiao-yan, CHEN Wei   

  1. Department of Geriatrics, Huashan Hospital, Fudan University, Shanghai 200040, China
  • Received:2007-05-31 Published:2007-09-01 Online:2007-09-01

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摘要： 目的探讨老年2型糖尿病与血清睾酮的相关性。方法选择1012例老年男性,分成糖尿病和非糖尿病组,测定两组体重指数(BMI)、收缩压(SBP)、舒张压(DBP)、空腹血糖(FBG)、餐后血糖(PBG)、甘油三酯(TG)、胆固醇(CHO)、高密度脂蛋白(HDL-C)、低密度脂蛋白(LDL-C)、空腹血清胰岛素(FINS)、餐后血清胰岛素(PINS)、血清睾酮(T)、雌二醇(E2)。结果与非糖尿病组相比,老年男性糖尿病组的FBG、PBG、FINS、PINS、TG、E2水平升高(P<0.05),而HDL-C、T水平降低(P<0.05)。多因素逐步回归分析显示影响T的因素从大到小依次为HDL-C、FINS、PINS和TG。结论TG、HDL-C、FINS、PINS与老年2型糖尿病男性的T水平密切相关。

关键词: 2型糖尿病, 睾酮, 老年, 男性

Abstract: Objective To explore the correlation between serum testosterone and type 2 diabetes mellitus in elderly male.Methods 1012 elderly male were divided into 2 groups according to their histry of DM.Blood glucose(FBG,PBG),cholesterol(CHO),triglyceride(TG),blood pressure(DBP,SBP),body mass index(BMI),serum insulin(FINS,PINS),serum testosterone(T)and estradiol(E2)were measured.Results Eldly male with type 2 diabetes showed higher FBG,PBG,TG,FINS,PINS and E2 level than those without DM(P<0.05),and with lower HDL-C and T level(P<0.05).The analysis of multiple stepwise regression showed that T level was correlated with the level of HDL-C,FINS,PINS and TG.Conclusion TG,HDL-C,FINS and PINS level correlate with T level in eldly male with type 2 diabetes mellitus.

Key words: type 2 diabetis mellitus, testosterone, the elderly, male