《中国康复理论与实践》

《中国康复理论与实践》 ›› 2007, Vol. 13 ›› Issue (08): 714-715.

• 专题　神经损伤康复 • 上一篇    下一篇

急性颈内或大脑中动脉闭塞患者临床预后分析

廖晓凌; 王伊龙; 王拥军; 薛静; 高培毅   

  1. 首都医科大学附属北京天坛医院神经内科; 首都医科大学附属北京天坛医院神经内科 北京市
  • 收稿日期:2006-10-23 出版日期:2007-08-01 发布日期:2007-08-01

Prognosis of Patients with Acute Internal Carotid Artery or Middle Cerebral Artery Occlusion

LIAO Xiao-ling, WANG Yi-long,WANG Yong-jun, et al   

  1. The Department of Neurology, Beijing Tiantan Hospital Affiliated to Capital Medical University, Beijing 100050, China
  • Received:2006-10-23 Published:2007-08-01 Online:2007-08-01

PDF (PC)

摘要： 目的探讨急性颈内或大脑中动脉闭塞的缺血性卒中患者的临床预后及预测结局的因素。方法选择发病6h内磁共振血管造影检查示颈内或大脑中动脉闭塞的患者48例,收集临床及影像学数据,在90d后评定患者的改良Ranking量表(mRS)评分,Logistic回归分析临床结局相关因素。结果48例患者临床结局好者(mRS0～2分)17例(35.4%),临床结局不良者(mRS3～6分)31例(64.6%),其中7例(14.6%)死亡。Logistic回归分析仅大面积梗死(OR=21.1,95%CI1.4～314.2,P=0.027)及高血糖(OR=5.1,95%CI1.3～19.8,P=0.019)同临床结局不良相关。结论急性颈内或大脑中动脉闭塞患者大部分临床预后较差,大面积梗死及高血糖是预测临床结局的独立因素。

关键词: 急性缺血性卒中, 磁共振血管造影, 预后

Abstract: Objective To investigate prognosis of acute ischemic patients with internal carotid artery or middle cerebral artery occlusion and define predictors of clinical outcome.MethodsThe clinical and radiological data of 48 stroke patients who underwent magnetic resonance angiography (MRA) within 6 hours of symptom onset and visualized internal carotid artery or middle cerebral artery occlusion on early MRA were analyzed. 90 days after onset, modified Ranking Scale (mRS) scores were obtained and factors related with prognosis were defined by logistic regression analysis.ResultsOf 48 patients, 17 cases (35.4%) got good clinical outcome (mRS 0～2), 31 cases (64.6%) got poor clinical outcome (mRS 3～6) with 7 cases (14.6%) died. In multivariate logistic regression analysis, only large infarction ( OR=21.1, 95%CI 1.4～314.2, P=0.027) and hyperglycaemia ( OR=5.1, 95%CI 1.3～19.8, P=0.019) were independent predictors of poor outcome.ConclusionClinical outcomes of most acute stroke patients with internal carotid artery or middle cerebral artery occlusion are poor. Large infarction and hyperglycaemia are independent predictors of clinical outcome.

Key words: acute ischemic stroke, magnetic resonance angiography, prognosis