《中国康复理论与实践》 ›› 2007, Vol. 13 ›› Issue (05): 486-487.

• 临床研究 • 上一篇    下一篇

阿米替林结合手法治疗发作性紧张性头痛的临床观察

陈志新1,3; 吴士文2; 马维娅2; 江亿平1   

  1. 1.解放军总医院康复科,北京市 100853;2.武警总医院神经内科,北京市 100039;3.八一体工队卫生队,北京市 100091
  • 收稿日期:2007-03-06 出版日期:2007-05-01 发布日期:2007-05-01

Effect of Amitriptyline with Manipulative Therapy on Episode Tension-type Headache

CHEN Zhi-xin, WU Shi-wen, MA Wei-ya,et al.   

  1. Department of Rehabilitation, the General Hospital of PLA, Beijing 100853, China
  • Received:2007-03-06 Published:2007-05-01 Online:2007-05-01

摘要: 目的观察阿米替林结合手法治疗发作性紧张性头痛的疗效。方法62例发作性紧张性头痛患者随机分成阿米替林组和阿米替林结合手法治疗组。所有患者均记录头痛日记。分别在治疗第2、4周时比较两组间疗效。结果在治疗后第1~2周内,阿米替林组和阿米替林结合手法治疗组头痛平均天数分别为(6.00±2.21)d和(4.19±1.70)d,第3~4周分别为(4.00±1.86)和(2.16±1.21)d,两组间均存在显著性差异(均P<0.05);在治疗后第3~4周,两组的视觉疼痛评定量表评分分别为(3.32±0.94)和(2.39±1.33),存在显著性差异(P<0.05);治疗后第1~2周服用止痛剂平均天数,治疗组与对照组分别为(1.77±1.23)d和(1.32±1.22)d,两组间存在显著差异(P<0.05),但在治疗后第3~4周时,这种差异消失。结论手法结合阿米替林治疗发作性紧张性头痛疗效优于单纯阿米替林治疗。

关键词: 手法治疗, 阿米替林, 紧张性头痛

Abstract: Objective To observe the clinical efficacy of amitriptyline with manipulative therapy for episode tension-type headache (ETTH). Methods 62 patients were randomized into 2 groups: amitriptyline group, amitriptyline with manipulative therapy group. Numbers of days with headache(NDH) and days with medication(NDM), intensity of the headache(IH) between the two weeks before randomisation and 1~2, 3~4 weeks after randomization were recorded by participants in headache diaries. Results In the first 2 weeks after treatment, the NDH in amitriptyline group and amitriptyline with manipulative therapy group were (6.00±2.21) d and (4.19±1.70) d respectively (P<0.05), while in the second 2 weeks, they were (4.00±1.86) d and (2.16±1.21) d respectively (P<0.05). The NDM in amitriptyline group and amitriptyline with manipulative therapy group were (1.77±1.23) d and (1.32±1.22) d respectively in the first 2 weeks after treatment (P<0.05), but there was no significantly difference between the two groups in the second 2 weeks. The IH (with Visual Analog Scale) were(3.32±0.94) and (2.39±1.33)respectively (P<0.05) in the second 2 weeks. Conclusion Amitriptyline with manipulative therapy is better than amitriptyline alone in reducing the symptoms of episode tension type headache.

Key words: manipulative therapy, amitriptyline, episode tension type headache