《中国康复理论与实践》

《中国康复理论与实践》 ›› 2007, Vol. 13 ›› Issue (05): 415-416.

• 专题　缺血性脑卒中 • 上一篇    下一篇

测定D-二聚体和超敏C-反应蛋白对急性脑梗死患者的临床意义

陈兵; 孟祥红; 耿晓非; 王卫; 陈娟; 魏东宁   

  1. 解放军总医院附属第二医院,北京市 100091
  • 收稿日期:2007-03-06 出版日期:2007-05-01 发布日期:2007-05-01

Clinical Significance of Measurment of D-Dimer and High Sensitive C-Reactive Protein in Serum for Acute Cerebral Infarction

CHEN Bing, MENG Xiang-hong, GENG Xiao-fei, et al   

  1. The Second Affiliated Hospital, General Hospital of PLA,Beijing 100091,China
  • Received:2007-03-06 Published:2007-05-01 Online:2007-05-01

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摘要： 目的探讨脑梗死患者血中D-二聚体和超敏C-反应蛋白(Hs-CRP)含量变化与脑梗死发生的关系。方法测定64例急性脑梗死患者和50名健康对照者血清中D-二聚体和Hs-CRP含量,并进行比较,同时对急性脑梗死患者进行美国卫生研究院卒中量表(NIHSS)评分。结果急性脑梗死患者D-二聚体和Hs-CRP含量明显高于对照组(P<0.05);大面积脑梗死组中D-二聚体和Hs-CRP含量明显高于小面积组(P<0.01);但D-二聚体和Hs-CRP含量与脑梗死患者NIHSS评分无相关性。结论测定血中D-二聚体和Hs-CRP含量对急性脑梗死的临床分析有价值。

关键词: 脑梗死, D-二聚体, 超敏C-反应蛋白, 美国卫生研究院卒中量表(NIHSS)

Abstract: Objective To explore the relationship of D-Dimer and high sensitive C-reactive protein in serum in acute cerebral infarction. Methods 64 patients with acute cerebral infarction were measured with the D-Dimer and Hs-CRP and compared with that of 50 healthy subjects as the controls. Their scores of National Institutes of Health Stroke Scale (NIHSS) were recorded and the correlation with the D-Dimer and Hs-CRP level was analyzed. Results Compared with those in controls, the levels of D-Dimer and Hs-CRP in patients with acute cerebral infarction were significantly higher (P<0.05), and those in patients with large infarction area were significantly higher than those in patients with small infarction area (P<0.01). The levels of D-Dimer and Hs-CRP uncorrelated with the scores of NIHSS.Conclusion The D-Dimer and Hs-CRP level is helpful to assess the acute cerebral infarction.

Key words: cerebral infarction, D-Dimer, high sensitive C-reactive protein(Hs-CRP), National Institutes of Health Stroke Scale (NIHSS)