《中国康复理论与实践》

《中国康复理论与实践》 ›› 2006, Vol. 12 ›› Issue (02): 152-153.

• 临床研究 • 上一篇    下一篇

通心方干预冠心病支架术后心肌缺血效果观察

冯其茂1; 董耀荣1; 杨祖福2   

  1. 1.上海市中医医院心内科 上海市 200071;2.北京博爱医院内科 北京市 100068
  • 收稿日期:2005-07-01 出版日期:2006-02-25 发布日期:2006-02-25

Effect of Tongxinfang on Coronary Collateral Formation and Stent-restenosis in Patients with Coronary Artery Disease after Stenting

FENG Qi-mao, DONG Yao-rong, YANG Zu-fu   

  1. The Department of Cardiac Internal Medicine, Shanghai Traditional Chinese Medicine Hospital, Shanghai 200071, China
  • Received:2005-07-01 Published:2006-02-25 Online:2006-02-25

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摘要： 目的观察中药对冠心病支架术后缺血心肌血管新生以及支架再狭窄的临床疗效。方法选择冠心病患者61例,随机分为治疗组30例和对照组31例,治疗组给予中药通心方,对照组采用基础治疗,疗程6个月。分别于治疗前和治疗6个月后,采用血管数字减影检测冠脉侧枝循环、支架再狭窄发生情况,同时采用二维超声心动图测量射血分数。结果治疗组患者的侧枝循环和射血分数的改善程度好于对照组(P<0.05,P<0.01),但最小管腔直径和管腔狭窄百分率与对照组无显著性差异(P>0.05)。结论中药通心方能改善冠心病患者的侧枝循环和射血分数。

关键词: 中药, 冠心病, 侧枝循环, 支架再狭窄

Abstract: ObjectiveTo observe the effect of Tongxinfang on coronary collateral formation and stent-restenosis in patients with coronary artery disease after stenting.Methods61 patients with coronary artery disease were randomly divided into the treatment group (n=30), and control group (n=31). Patients of the treatment group were taking Chinese medicine Tongxinfang for six months, but cases of the control group only received basic treatment. Coronary collateral formation, stent-restenosis and ejection fraction (EF) of patients of two groups were assessed through aniograms and echocardiography before treatment and after six months.ResultsCoronary collateral formation and EF of patients of the treatment group improved significantly compared with cases of the control group (P<0.01 or P<0.05), but the minimal lumen diameter and percent of diamter stenosis were not significantly different between two groups (P>0.05).ConclusionTongxinfang can improve coronary collateral formation and EF.

Key words: traditional Chinese medicine, coronary artery disease, collateralization, stent-restenosis