《中国康复理论与实践》

《中国康复理论与实践》 ›› 2007, Vol. 13 ›› Issue (01): 53-55.

• 综述 • 上一篇    下一篇

低频振动对成骨作用的影响

叶超群1,2; 纪树荣3; 史清钊1   

  1. 1.首都体育学院保健康复教研室,北京市 100088;2.北京军区总医院骨科,北京市 100068;3.北京博爱医院,北京市 100700
  • 收稿日期:2006-05-15 出版日期:2007-01-01 发布日期:2007-01-01

Application of Low Frequency Vibration in Osteogenesis

YE Chao-qun, JI Shu-rong, SHI Qing-zhao   

  1. Teaching& Research Section of Health Care and Recovery, Capital Institute of Physical Education, Beijing 100088, China
  • Received:2006-05-15 Published:2007-01-01 Online:2007-01-01

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摘要： 应力是调节骨生长与重建的重要因素,低频振动是软科学刺激之一,具有良好的促进骨形成作用,其成骨效果受振动频率、方式、强度影响。低频振动促进骨形成作用的机制可能与细胞膜离子通道、整合素-细胞骨架复合体激活促细胞分裂剂活化蛋白激酶途径、第二信使调节RANK-RANKL-OPG轴有关。

关键词: 低频振动, 骨形成, 综述

Abstract: Mechanical loading provides an anabolic stimulus for bone. Low frequency vibration is a kind of mechanic stimulus, which can promote osteogenesis in certain frequency, mode and intensity. The osteogenesis promotion of low frequency vibration may be associated with the membrane ion channels, integrin-cytoskeleton complex triggering mitogen activated protein kinase (MAPK) signal and second messengers regulating RANK-RANKL-OPG axals.

Key words: low frequency vibration, osteogenesis, review