《中国康复理论与实践》

《中国康复理论与实践》 ›› 2005, Vol. 11 ›› Issue (10): 797-798.

• 专题 • 上一篇    下一篇

巴曲酶治疗糖尿病合并急性脑梗死的临床观察

于棉荣; 鲍瑞雪; 孟庆江   

  1. 北京博爱医院急诊科 北京市 100068
  • 收稿日期:2005-06-06 出版日期:2005-10-25 发布日期:2005-10-25

Clinical observation of Batroxobin on the diabetics complicated with acute cerebral infarction

YU Mian-rong, BAO Rui-xue, MENG Qing-jiang   

  1. The Department of Emergency, The Beijing Charity Hospital, Beijing 100068, China
  • Received:2005-06-06 Published:2005-10-25 Online:2005-10-25

PDF (PC)

摘要： 目的观察静脉注射巴曲酶治疗糖尿病合并脑梗死的有效性和安全性。方法对66例糖尿病合并脑梗死患者采用静脉注射巴曲酶治疗;于治疗前、治疗后3d和6d进行神经功能缺损评分,同时进行凝血功能、血小板计数等实验室检查。结果66例患者治疗后血浆纤维蛋白原浓度显著降低(P<0.001),神经功能缺损评分显著改善(P<0.001),总有效率为93.9%;未见药物不良反应。结论早期巴曲酶静脉滴注可作为糖尿病合并急性脑梗死早期溶栓治疗的方法之一。

关键词: 巴曲酶, 糖尿病, 急性脑梗死, 合并症, 溶栓

Abstract: ObjectiveTo observe the effect and security of Batroxobin vein injection on patients with diabetes mellitus and acute cerebral infarction.Methods66 patients with diabetes mellitus and acute cerebral infarction were treated with Batroxobin vein injection and assessed with the scale of neurological deficit before treatment and at 3rd and 6th day after treatment.At the same time the coagulant function and the count of blood platelet were measured.ResultsAfter treatment,the concentration of fibrinogen in blood plasma of patients decreased and scores of neurological deficit assessment improved both significantly(P<0.001).The total validity of Batroxobin vein injection was 93.9%.No side actions of drug were found.ConclusionBatroxobin vein injection can be used as a therapeutic method of dissolving thrombus in patients with diabetes mellitus and acute cerebral infarction in early stage.

Key words: Batroxobin, diabetes mellitus, acute cerebral infarction, complication, dissolving thrombus