《中国康复理论与实践》

《中国康复理论与实践》 ›› 2008, Vol. 14 ›› Issue (11): 1009-1010.

• 专题　神经泌尿康复 • 上一篇    下一篇

帕金森病性神经原性膀胱功能障碍

梁文立1,2; 廖利民1,2   

  1. 1.首都医科大学康复医学院,北京市 100068;2.中国康复研究中心北京博爱医院泌尿外科,北京市 100068
  • 收稿日期:2008-11-05 出版日期:2008-11-01 发布日期:2008-11-01

Neurogenic Bladder Disorder after Parkinson Disease (review)

LIANG Wen-li, LIAO Li-min   

  1. Capital Medical University School of Rehabilitation Medicine, Department of Urology, Beijing Charity Hospital, China Rehabilitation Research Centre, Beijing 100068, China
  • Received:2008-11-05 Published:2008-11-01 Online:2008-11-01

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摘要： 帕金森病(PD)是一种中老年人常见的缓慢进展性运动障碍疾病。35%～70%的PD患者会出现排尿症状,且常出现于疾病的后期。尿流动力学表现为逼尿肌的过度活动和反射性尿失禁。目前治疗主要有抗胆碱能药物和膀胱内灌注药物或肉毒素膀胱逼尿肌多点注射。其发生和治疗效果和多巴能神经元的损耗相关,但其机制仍需进一步阐明。

关键词: 帕金森病, 尿动力学, 神经原性膀胱, 综述

Abstract: Parkinson disease (PD) is one of the common neurological conditions with chronically progressed dyskinesis. 35%～70% of them are perplexed by micturition disorder, which frequently occurs in advanced stage. Urodynamics shows detrusor's overactivity and reflexic incontinence complete voiding. Treament at present includes mainly anticholinergic agents, infusing agents in bladder and/or Botulinum toxin multipoint injections to detrusor. Its genesis and effect is related to deterioration of dopaminergic neurons, hovever, and the mechanism is needed to be elucidated.

Key words: Parkinson disease, urodynamics, neurogenic bladder, review