《中国康复理论与实践》

《中国康复理论与实践》 ›› 2008, Vol. 14 ›› Issue (11): 1003-1004.

• 专题　神经泌尿康复 • 上一篇    下一篇

硝酸甘油对脊髓损伤雌性大鼠漏尿点压力影响的初步研究

叶云龙1,2; 廖利民1,2; 鞠彦合1,2; 吕振1,2   

  1. 1.首都医科大学康复医学院,北京市 100068;2.中国康复研究中心北京博爱医院泌尿外科,北京市 100068
  • 收稿日期:2008-11-05 出版日期:2008-11-01 发布日期:2008-11-01

Effects of Nitroglycerin on Leak Point Pressure of Spinal Cord Injury Female Rats

YE Yun-long, LIAO Li-min, JU Yan-he, et al   

  1. Capital Medical University School of Rehabilitation Medicine, Department of Urology, Beijing Charity Hospital, China Rehabilitation Research Centre, Beijing 100068, China
  • Received:2008-11-05 Published:2008-11-01 Online:2008-11-01

PDF (PC)

被引次数

1

摘要： 目的初步探讨硝酸甘油对慢性期完全性脊髓损伤雌性大鼠漏尿点压力的影响。方法建立慢性期完全性脊髓损伤雌性大鼠模型,腹腔注射硝酸甘油3mg。观察用药前后大鼠逼尿肌漏尿点压力的变化。结果用药前漏尿点压力(32.27±15.00)cm H2O(1cm H2O=98.0665Pa),用药后为(23.29±9.46)cm H2O(P≤0.01)。结论腹腔注射硝酸甘油可明显降低慢性期完全性脊髓损伤雌性大鼠漏尿点压力。

关键词: 脊髓损伤, 硝酸甘油, 一氧化氮, 漏尿点压力

Abstract: Objective To study the effects of nitroglycerin on leak point pressure of chronic complete spinal cord injury female rats. Methods Models of chronic complete spinal cord injury in female rats were established. Changes of leak point pressure were investigated following nitroglycerin 3 mg intraperitoneal injection. Results Leak point pressure decreased from (32.27±15.00) cmH2O to (23.29±9.46) cmH2O. Conclusion There was obvious descent of leak point pressure of chronic complete spinal cord injury female rats following nitroglycerin intraperitoneal injection.

Key words: spinal cord injury, nitroglycerin, nitric oxide, leak point pressure