《中国康复理论与实践》 ›› 2005, Vol. 11 ›› Issue (08): 667-668.

• 临床观察 • 上一篇    下一篇

桥脑及桥脑外髓鞘溶解症4例分析

何静杰; 杜敏; 朱镛连; 徐建民   

  1. 1.北京博爱医院神经内科 北京市 100068;2.湖北省中山医院神经内科 湖北武汉市 430030;3.北京博爱医院影像科 北京市 100068
  • 收稿日期:2005-02-21 出版日期:2005-08-25 发布日期:2005-08-25

Analysis of 4 cases with central pontine myelinolysis and extral pontine myelinolysis

HE Jing-jie, DUMin, ZHU Yong-lian, et al   

  1. The Department of Neurology, Beijing Charity Hospital, Beijing 100068, China
  • Received:2005-02-21 Published:2005-08-25 Online:2005-08-25

摘要: 目的探讨桥脑中央髓鞘溶解症(CPM)的病因、诊断和康复治疗。方法回顾性分析4例CPM的临床资料。结果4例均表现为假性延髓麻痹、肌张力增高;3例有意识不清;2例发生在低钠血症被快速纠正之后;1例发生在高钠血症被快速纠正之后。4例均经头颅MRI检查显示桥脑脱髓鞘病灶,其中3例同时显示脑干外病灶。4例预后均良好。结论低钠血症被快速纠正是CPM的常见原因,综合康复治疗可以改善预后,提高生活质量。

关键词: 桥脑中央髓鞘溶解症(CPM), 磁共振成像(MRI), 康复治疗

Abstract: ObjectiveTo explore the pathogeny, diagnosis and rehabilitation of central pontine myelinolysis.MethodsClinical data of four patients with central potine myelinolysis were studied retrospectively.ResultsAll of them had pseudobulbar palsy and dystonia; three had coma; two had history of hyposodemia ameliorated rapidly, one had history of hypersodemia ameliorated rapidly. All of them had focuses in pons; three had focuses beyond pons. All patients had good prognoses.ConclusionHistory of hyposodemia ameliorated rapidly is a usual pathogeny of central potine myelinolysis, integrative measures of rehabilitation can improve prognosis and quality of daily life.

Key words: central pontine myelinolysis (CPM), magnetic resonance imaging (MRI), rehabilitation