《中国康复理论与实践》

《中国康复理论与实践》 ›› 2005, Vol. 11 ›› Issue (06): 483-484.

• 临床研究 • 上一篇    下一篇

高度近视黄斑区脉络膜新生血管光学相干断层扫描分析

王炜; 何守志; 崔霞   

  1. 解放军总医院眼科 北京市 100853
  • 收稿日期:2005-01-24 出版日期:2005-06-25 发布日期:2005-06-25

Optical coherence tomography features of myopia

WANG Wei, HE Shou-zhi, CUI Xia   

  1. The Department of Ophthalmology, The General Hospital of PLA, Beijing 100853, China
  • Received:2005-01-24 Published:2005-06-25 Online:2005-06-25

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摘要： 目的探讨高度近视黄斑部视网膜下脉络膜新生血管(CNV)患者的光学相干断层扫描(OCT)图像特征。方法对16例(17眼)病理性高度近视连续治疗患者进行OCT检查,并与荧光素眼底血管造影(FFA)和吲哚青绿眼底血管造影(ICGA)结果进行对比;同时对光动力治疗后患者的OCT图像形态变化进行分析。结果17眼中有12眼CNV呈类圆形团块状,自视网膜色素上皮层向上突出,位于视网膜神经上皮下间隙,呈强或中等强度反射;5眼的CNV呈纺锤形或不规则形,亦呈强或中等强度反射,位于色素上皮层平面。17眼中9眼伴浆液性神经上皮脱离,11眼伴出血性色素上皮脱离,14眼伴不同程度视网膜水肿和增厚。12眼经光动力治疗(PDT)后,FFA检查显示荧光素渗透消退或减弱,OCT检查显示CNV团块不同程度退缩,形态亦发生变化。结论OCT检查可确定高度近视黄斑病变中CNV团块的形态、大小及位置。高度近视黄斑病变中CNV的OCT图像以突出于色素上皮层的类圆形团块为特征,形态和大小可因治疗和观察时间而变化。

关键词: 高度近视, 脉络膜新生血管, 视网膜疾病, 吲哚花青绿, 荧光素血管造影术

Abstract: ObjectiveTo explore the morphological features of macular subretina choroidal neovascularization (CNV) in high myopia with optical coherence tomography (OCT).Methods16 CNV cases (17 eyes) were examined with OCT, and compared with results of fundus fluorescein angiography (FFA) and indocyanine green angiography (ICGA).ResultsCNV appeared in space under sensory retinal anterior to the retinal pigment epithelium in 12 of 17 eyes. In 5 eyes, CNV appeared as a highly reflective fusiform or irregular mass at the level of retinal pigment epithelium and choriocapillaris. 9 of 17 eyes were associated with serous neurosensory retinal detachment, 11 eyes with hemorrhagic pigment epithelium detachment (PED) and 14 eyes with edema and thickening of sensory retina. 12 eyes regressed and its morphological features changed after photo dynamical therapy (PDT).ConclusionOCT can be used to confirm the morphological features, location and size of submacular CNV. CNV appears as a highly or moderately reflective round mass which protrudes from the retinal pigment epithelium in most cases. The morphology and the size of this mass may change after treatment and during follow-up.

Key words: high myopia, choroidal neovascularization (CNV), retinal diseases, indocyanine green, fluorescein angiography