《中国康复理论与实践》

《中国康复理论与实践》 ›› 2005, Vol. 11 ›› Issue (06): 481-482.

• 临床研究 • 上一篇    下一篇

枢丹联用地塞米松治疗血液病患者化疗性呕吐疗效观察

周亚红; 唐菊英; 贾博军; 汤春静   

  1. 解放军总医院血液科 北京市 100853
  • 收稿日期:2005-08-15 出版日期:2005-06-25 发布日期:2005-06-25

Clinical observation of the ondanseton and dexamethone treatment for vomiting during hematologic diseases chemotherapy

ZHOU Ya-hong, TANG Ju-ying, JIA Bo-jun, et al   

  1. The General Hospital of PLA, Beijing 100853, China
  • Received:2005-08-15 Published:2005-06-25 Online:2005-06-25

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摘要： 目的控制血液病患者化疗性恶心呕吐,减轻患者痛苦,使化疗顺利进行。方法将320例血液病患者随机分为2组。治疗组(160例):枢丹4mg+地塞米松10mg静推;枢丹组(160例):枢丹4mg静推。结果止吐有效率治疗组98.75%,枢丹组43.13%,两组间有非常高度显著性差异(P<0.001)。结论枢丹联用地塞米松对化疗引起的恶心呕吐有较好的疗效。

关键词: 血液病, 化疗, 止呕药

Abstract: ObjectiveTo relieve the nausea and vomiting caused by chemotherapy in patients with hematologic diseases, and to secure the completion of chemotherapy.Methods320 cases of hematologic patients were divided randomly into 2 groups: the treatment group (160 cases): ondanseton 4 mg and dexamethone 10 mg I.V.; ondanseton group (160 cases): ondanseton 4 mg I.V.ResultsThe effective rate of the treatment group was 98.75%, and that of the ondansetron group was 43.13%. There was a singificantly difference between two groups (P<0.001).ConclusionOndanseton combined with dexamethone has a good effect on the vomiting and nausea induced by chemotherapy.

Key words: hematologic diseases, chemotherapy