《中国康复理论与实践》

《中国康复理论与实践》 ›› 2005, Vol. 11 ›› Issue (06): 475-476.

• 临床研究 • 上一篇    下一篇

TUR-Bt术后膀胱内灌注鸦胆子油乳预防浅表性膀胱癌复发

田丰1; 王禾1; 秦卫军1; 朱开常2; 刘悦2; 黄亮2   

  1. 1.第四军医大学西京医院泌尿外科 陕西西安市 710032;2.解放军第210医院泌尿外科 辽宁大连市 116023
  • 收稿日期:2005-04-21 出版日期:2005-06-25 发布日期:2005-06-25

Preventing superficial bladder cancer from recurrence by intravesical instillation with Brucea Javanica oil emulsion after TUR-Bt operation

TIAN Feng, WANG He, QIN Wei-jun, et al   

  1. The Department of Urinary Surgery, The Xijing Hospital of the Fourth Military Medicine University, Xian710032, Shanxi, China
  • Received:2005-04-21 Published:2005-06-25 Online:2005-06-25

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摘要： 目的观察鸦胆子油乳膀胱灌注预防浅表性膀胱癌经尿道膀胱肿瘤电切术(TUR-Bt)术后复发的疗效。方法187例浅表性膀胱癌TUR-Bt术后患者随机分为A组(85例)和B组(102例),A组应用鸦胆子油乳膀胱灌注,B组灌注丝裂霉素预防肿瘤复发。对两组患者随访3年,观察肿瘤复发及药物副作用情况。结果A组复发11例,复发率12.94%,较B组的34.31%显著降低(P<0.001),且副作用小(P<0.001)。结论TUR-Bt术后灌注鸦胆子油乳预防膀胱癌复发有良好效果。

关键词: 膀胱肿瘤, 膀胱内灌注, 鸦胆子, 复发, 经尿道膀胱肿瘤电切术(TUR-Bt)

Abstract: ObjectiveTo observe the effect of intravesical instillation of Brucea Javanica oil emulsion on recurrence of bladder cancer after transurethral resection of bladder tumor (TUR-Bt) operation.Methods187 patients with superficial bladder carcinoma after TUR-Bt operation were randomly divided into the group A (85 cases) and group B (102 cases). Patients of the group A were treated with instillation of Brucea Javanica oil emulsion; those of the group B were treated with mitomycin. A three-years following up was performed to observe the recurrence and side effects.ResultsAfter a 3-years following up, the recurrence rate of group A was 12.94%, lower than that of group B (34.31%). The side effects were seldom seen in the group A.ConclusionThe effect of intravesical instillation of Brucea Javanica oil emulsion to prevent the recurrence of bladder cancer after TUR-Bt operation is favorable.

Key words: bladder neoplasms, intravesical instillation, Brucea Javanica, recurrence, Transurethral resection of bladder tumor (TUR-Bt)