《中国康复理论与实践》 ›› 2005, Vol. 11 ›› Issue (05): 402-403.

• 临床观察 • 上一篇    下一篇

妥泰引起严重认知障碍

孙伟; 王薇薇; 吴逊   

  1. 北京大学第一医院神经内科 北京市 100034
  • 收稿日期:2005-01-13 出版日期:2005-05-25 发布日期:2005-05-25

Severe cognitive deficit caused by Topiramate

SUN Wei,WANG Wei-wei,WU Xun   

  1. Department of Neurology,Peking University First Hospital,Beijing 100034,China
  • Received:2005-01-13 Published:2005-05-25 Online:2005-05-25

摘要: 目的探讨癫痫患者服用妥泰出现严重认知障碍的特点。方法对3 例服用妥泰后出现严重认知障碍的癫痫患者的临床资料进行总结。结果与结论多表现为语言功能受损,尤其是语言流畅性受损,而严重认知障碍的患者除了上述表现外,还伴有严重记忆力、计算力障碍。

关键词: 妥泰, 癫痫, 认知障碍, 副作用

Abstract: ObjectiveTo investigate the character of severe cognitive deficit caused by topiramate(TPM) administration in epileptic patients.Methods3 epileptic patients who suffered from severe cognitive deficit following topramate treatment were analyzed.Results and ConclusionTheir verbal functions were often affected especially the fluency of speech, as well as their memory and calculation.

Key words: Topiramate, epilepsy, cognitive deficit, side effect