《中国康复理论与实践》 ›› 2005, Vol. 11 ›› Issue (05): 386-387.

• 临床研究 • 上一篇    下一篇

脑外伤后综合征与重型颅脑外伤的脑血流和血液流变学研究

刘诗翔; 刘波; 梁燕; 王文富   

  1. 成都军区昆明总医院神经内科 云南昆明市 650032
  • 收稿日期:2005-02-24 出版日期:2005-05-25 发布日期:2005-05-25

Clinical study of brain post-traumatic syndrome and heavy cerebral trauma with hemorheology and transcranial Doppler

LIU Shi-xiang, LIUBo, LIANG Yan, et al   

  1. Department of Neurology,Kunming General Hospital, Kunming 650032, Yunnan, China
  • Received:2005-02-24 Published:2005-05-25 Online:2005-05-25

摘要: 目的研究脑外伤后综合征(PTS)和重型颅脑外伤的脑血流、血液流变学的变化规律。方法PTS组122 例为A组,重型颅脑外伤组113例为B组,采用经颅多普勒分别探测大脑中(MCA)、前(ACA)、后动脉(PCA)和椎动脉(VA)、基底动脉(BA)。检查全血粘度、血浆粘度和红细胞变形指数。结果PTS患者左右半球各动脉与重型颅脑外伤相比主要表现为血流缓慢,以MCA、ACA、VA、BA更为明显。A组左半球MCA和VA血流缓慢比右半球明显,B组左右半球血管痉挛无差异。2 组患者均有明显的全血粘度增高、血浆粘度增高和RBC变形性降低。结论PTS存在器质性脑损伤,以左半球为主,TCD主要表现为血流缓慢;PTS患者和重型颅脑外伤患者均存在严重的血液流变学异常。

关键词: 脑外伤后综合征, 颅脑外伤, 经颅多普勒超声(TCD), 血液流变学

Abstract: ObjectiveTo study the change of cerebral blood flow and hemorheology in patients with brain post-traumatic syndrome (PTS) and heavy cerebral trauma.Methods122 cases(A group) of PTS and 113 cases(B group) of heavy cerebral trauma were explored the anterior cerebral artery (ACA),middle cerebral artery (MCA),posterior cerebral artery (PCA),vertebral artery (VA) and basilar artery (BA) with transcranial Doppler (TCD). Their blood viscosity, plasm viscosity, red blood cell (RBC) deformed exponent were also measured.ResultsThe blood stream in most of patients with PTS manifested slowing especially in MCA,ACA,VA and BA at left. However,most of patients with heavy cerebral trauma manifested vasospasm. The blood and plasm viscosity of both groups obviously increased, but RBC deformed exponent decreased.ConclusionPatients with PTS suffered organic brain damage, mainly in levo-hemisphere.The patients with PTS or with heavy cerebral trauma present disorder in hemorheology.

Key words: post-traumatic syndrome, cerebral trauma, transcranial Doppler(TCD), hemorheology