《中国康复理论与实践》

《中国康复理论与实践》 ›› 2004, Vol. 10 ›› Issue (07): 425-426.

• 临床研究 • 上一篇    下一篇

神经节苷酯治疗小儿脑性瘫痪临床观察

张清华1; 赵勇2; 吴勇2; 孙秀玲2; 李雪琴2   

  1. 1.佛山市顺德区妇幼保健院,顺德区小儿神经疾病治疗中心 广东佛山市 528300;2.淮北市人民医院儿科脑瘫中心 安徽淮北市 235000
  • 收稿日期:2003-12-30 出版日期:2004-07-25 发布日期:2004-07-25

Effect of monosialo-gangliosides on cerebral palsy of childen

ZHANG Qing-hua, ZHAO Yong, WU Yong, et al   

  1. Department of Pediatrics, Woman and Children Hospital of Shunde, Foshan 528300, Guangdong, China
  • Received:2003-12-30 Published:2004-07-25 Online:2004-07-25

PDF (PC)

被引次数

44

摘要： 目的观察神经节苷酯治疗小儿脑性瘫痪(CP)的疗效。方法将87例CP患儿随机分为观察组(51例)和对照组(36例),予以物理疗法、针灸、按摩、高压氧等综合治疗,观察组患儿同时静脉滴注神经节苷酯(GM-1)。采用Gesell发育量表测评治疗前后两组患儿发育商(DQ),比较两组间疗效差异。结果观察组患儿疗效优于对照组(P<0.05),其大运动、精细运动、语言及DQ值均高于对照组(P<0.05)。结论神经节苷酯可提高CP的康复疗效。

关键词: 脑性瘫痪, 神经节苷酯, 发育商

Abstract: Objective To observe the therapeutic effectiveness of monosialo gangliosides injection (GM-1) on cerebral palsy (CP) of children.Methods 87 children with CP were randomly divided into the observation group (51 cases) and control group (36 cases), and treated with physical therapy, acupuncture, massage and hyperbaric oxygen, but monosialo gangliosides was added to the observation group only. The development quotient (DQ) of each group was calculated by Gesell development schedules before and after the therapy respectively. Therapeutic effects of two groups were compared.Results The therapeutic effect of the observation group was more satisfactory than that of control group(P<0.05). The observation group expressed higher DQ and scores of gross motor, fine motor, language and reaction than that of control group. Conclusion Monosialo ganglioside is effective on CP.

Key words: cerebral palsy, monosialo-gangliosides, development quotient (DQ)