《中国康复理论与实践》 ›› 1996, Vol. 2 ›› Issue (01): 12-17.

• 理论与实践 • 上一篇    下一篇

体内可分解性高分子材料的研究Ⅲ丙交酯乙交酯共聚反应条件的影响

张颖; 威文淑; 朴东旭   

  1. 中国康复研究中心康复医学研究所高分子室
  • 收稿日期:1995-08-24 出版日期:1996-03-25 发布日期:1996-03-25

Studies on Biodegradable Polymers Ⅲ Effect of Lactide-Glycolide Copolylnerization Reaction Condition

Zhang Ying,Xian Wenshu,Piao Dongxu   

  1. Chinese Journal of Rehabilitation Theory & Practice.-1996,2(1):12~17
  • Received:1995-08-24 Published:1996-03-25 Online:1996-03-25

摘要: 本文以辛酸亚锡为引发剂,十二烷醇为调节剂,进行丙交酯、乙交酯共聚。讨论了反应温度、反应时间、引发剂浓度、分子量调节剂、单体配比等反应条件对聚合转化率、分子量及其分布的影响。实验结果表明:引发剂含量0.075%、反应温度170℃、反应时间6hr为最佳反应条件,这时分子量、转化率都很高。

关键词: 丙交酯乙交酯共聚物, 分子量, 聚合转化率, 反应条件

Abstract: Lactide一glycolide copolymerization with stannous octanoate as an initiator and dedecanolas regulator was carried out.The effect of reaction condition such as reaction time,temperature, initiatorconcentration, regulator and monomer ratbonpolymerization conversion,molecular weight and its distrbu-tion were investigated.The obtained results show that the finest reaction condition are initiator 0. 075%,ternperature 170℃ and reaction time 6hr.At this reaction condition,both molecular weight and polymer-ization conversion obtained are vecy high.

Key words: Lactide一glycolide copolymer, molecular weight, conversion, reaction condition