《中国康复理论与实践》

《中国康复理论与实践》 ›› 2009, Vol. 15 ›› Issue (05): 476-478.

• 临床研究 • 上一篇    下一篇

老年肺部感染并发多器官功能不全综合征169例临床研究

谭清武   

  1. 解放军白求恩国际和平医院干部病房三科，河北石家庄市 050082
  • 收稿日期:2009-03-16 出版日期:2009-05-01 发布日期:2009-05-01

Multiple Organ Dysfunction Syndrome after Pulmonary Infection in Elderly: 169 Case Report

TAN Qing-wu   

  1. Bethune International Peace Hospital, Shijiazhuang 050082, Hebei, China
  • Received:2009-03-16 Published:2009-05-01 Online:2009-05-01

PDF (PC)

被引次数

13

摘要： 目的 探讨肺部感染并发老年多器官功能不全综合征（MODSE）的临床特点。方法 对2001年1月～2006年12月在我院住院的169例肺部感染并发MODSE进行回顾性分析。结果 169例病例均有1种以上的慢性基础疾病，82.9%的病例有4种以上慢性基础疾病，最多者有11种慢性基础疾病。首衰器官涉及肺、心、肾、胃肠等4个器官，其中以肺居首位；原有功能受损器官的首衰率显著高于原有功能未受损器官（P＜0.001）；二分类逐步Logistic回归分析显示MODSE分期、肾衰竭和外周循环衰竭是肺部感染并发MODSE死亡的危险因素（P＜0.05）。结论 肺和其他功能受损的器官是肺部感染并发MODSE的首衰器官；MODSE分期、肾衰竭和外周循环衰竭是肺部感染并发MODSE的死亡危险因素。及早发现和救治处于衰竭前期阶段的病例，有效保护和改善各器官功能，特别是加强对肾功能和外周循环功能的保护和改善，有可能降低MODSE的死亡率。

关键词: 多器官功能不全综合征（MODS）, 多器官功能衰竭, 肺部感染, 老年人

Abstract: Objective To explore the clinical feature of multiple organ dysfunction syndrome in the elderly (MODSE) induced by pulmonary infection. Methods The clinical sign of 169 cases with MODSE induced by pulmonary infection admitted from January 2001 to September 2006 were reviewed. Results All cases complicated more than one chronic disease. 82.9% cases complicated more than 4 chronic diseases. The first failure organ of MODSE induced by pulmonary infection included lung, heart, kidney or gastrointestinal tract, and the respiratory failure was the most commonly. The incidence of primary failure in organs dysfunction group was significantly higher than those in organs normal function group (P<0.001). Binary Logistic stepwise regression showed that clinical stage of MODSE, renal failure and circulatory failure were the high risk factors for mortality （P＜0.05）. Conclusion Lung or other dysfunction organs is the first failure organ in MODSE induced by pulmonary infection in most cases. Clinical stage of MODSE, renal failure and circulatory failure were the high risk factors for mortality. The mortality of MODSE may be reduced by preventing renal failure and circulatory failure.

Key words: multiple organ dysfunction syndrome, multiple organ failure, pulmonary infection, elderly