《中国康复理论与实践》 ›› 2009, Vol. 15 ›› Issue (03): 274-275.

• 临床研究 • 上一篇    下一篇

小儿小脑星形细胞瘤101例分析

李大鹏;齐巍;王稳恒;张力伟;张玉琪;甲戈;马振宇   

  1. 首都医科大学附属北京天坛医院神经外科,北京市 100050
  • 收稿日期:2008-12-26 出版日期:2009-03-01 发布日期:2009-03-01
  • 通讯作者: 马振宇

Pediatric Cerebellar Astrocytomas: 101 Cases Report

LI Da-peng, QI Wei, WANG Wen-heng, et al   

  1. Department of Neurosurgery, Bejing Tiantan Hospital, Capital Medical University, Bejing 100050, China
  • Received:2008-12-26 Published:2009-03-01 Online:2009-03-01

摘要: 目的 探讨小儿小脑星形细胞瘤的临床特征、治疗策略和预后。方法 回顾性分析101例经病理学证实的小儿星形细胞瘤病例的临床资料,并进行随访。结果 男性50例,女性51例,平均年龄9.8岁。肿瘤大小3~7.5 cm。实性瘤体型46例,瘤在囊内型24例,囊在瘤内型31例;39例位于小脑蚓部,62例位于小脑半球,9例位于第四脑室并与脑干粘连。手术全切除92例,近全切除9例。87例患者获得随访,随访时间为1~5年,术后生存率100%。所有病例均未接受放、化疗。结论 小儿小脑星形细胞瘤多发生于小脑半球,小脑蚓部也不少见,影像学和组织病理有助于诊断。治疗应以显微手术全切除为主,单纯手术全切除远期预后良好。

关键词: 小儿小脑星形细胞瘤, 治疗, 预后

Abstract: Objective To investigate the clinical features, therapeutic strategy and prognosis of pediatric benign cerebellar astrocytomas (BCAs). Methods 101 children with BCAs diagnosed histopathologically were analyzed retrospectively and followed up. Results There were 50 boys and 51 girls with a median age of 9.8 years old. The sizes of tumors were 3~7.5 cm. 46 cases were with solid-tumor, 24 with the tumor in the cyst, 31 with the cysty in the tumor. 39 cases were located in cerebellum vermis, 58 cases were in the cerebellar hemisphere and 9 cases were adhesive with brain stem located in the forth ventricle. 92 cases were total removed and 9 cases were subtotal removed. 87 patients were followed up for 1~5 years, and all of them has survived, without radiotherapy or chemotherapy. Conclusion Pediatric benign cerebellar astrocytomas mostly grows in cerebellar hemisphere, also in vermis frequently. Neuroimaging and pathology may conduce to the diagnosis. Microsurgical resection may result in optimal outcome.

Key words: pediatric benign cerebellar astrocytomas, treatment, prognosis