《中国康复理论与实践》

《中国康复理论与实践》 ›› 2009, Vol. 15 ›› Issue (03): 270-271.

• 临床研究 • 上一篇    下一篇

脑钠尿肽在老年人非心脏手术后的变化及意义

肖军1a;唐发宽1a;张伟1a;常青1b;关长勇1b;杨波1c;郑方1d   

  1. 1.解放军总医院第二附属医院,a.心内科;b.骨科;c.普外科;d肝胆外科，北京市 100091
  • 收稿日期:2008-12-19 出版日期:2009-03-01 发布日期:2009-03-01

Variance of Brain Natriuretic Peptide in Aged Patients after Noncardiac Surgery and Its Significance

XIAO Jun, TANG Fa-kuan, ZHANG Wei, et al   

  1. Department of Cardiology, the Second Affiliated Hospital of Chinese PLA General Hospital, Beijing 100091, China
  • Received:2008-12-19 Published:2009-03-01 Online:2009-03-01

PDF (PC)

被引次数

9

摘要： 目的 探讨血浆脑钠尿肽（BNP）浓度在老年人非心脏手术后的变化及意义。方法 依据术前血浆BNP浓度将101例择期行非心脏手术患者分为两组，A组(n=61)：BNP浓度≤100 ng/L；B组(n=40)：BNP浓度>100 ng/L，对比分析手术前后BNP浓度及术后心脏事件的发生情况。结果 A组术前、术后BNP浓度分别为（58.2±28.7） ng/L、(53.7±25.9) ng/L(P>0.05)；B组术前、术后BNP浓度分别为(147.3±72.1) ng/L、(341.5±92.4) ng/L（P<0.05）。A组无心脏事件发生，B组中有14例发生心脏事件（P<0.05）。结论 术前血浆BNP浓度>100 ng/L的老年人非心脏手术后血浆BNP浓度变化大，可能发生心脏事件。

关键词: 老年人, 脑钠尿肽(BNP), 非心脏手术, 心脏事件

Abstract: Objective To explore the variance of plasma brain natriuretic peptide (BNP) concentrations in the aged patients after noncardiac surgery and its significance. Methods 101 patients undergoing elective noncardiac surgery were divided into two groups based on the BNP concentrations before surgery: group A: BNP≤100 ng/L，n=61; group B: BNP>100 ng/L，n=40. The BNP concentrations before and after noncardiac surgery and the incidence of cardiac events in both groups were compared. Results There was no significant difference （P>0.05） of BNP concentrations before and after noncardiac surgery in group A, which were (58.2±28.7) ng/L and (53.7±25.9) ng/L respectively, but was significant difference （P<0.05） in group B, which were (147.3±72.1) ng/L and (341.5±92.4) ng/L respectively. There was significant difference （P<0.05） between group A, in which no patient happened cardiac event, and group B, in which 14 patients happened. Conclusion The plasma BNP concentration would be increased significantly in the aged patients with a BNP concentration>100 ng/L before surgery, which may cause more cardiac events.

Key words: aged, brain natriuretic peptide (BNP), noncardiac surgery, cardiac events