《中国康复理论与实践》 ›› 2009, Vol. 15 ›› Issue (07): 619-620.

• 专题 • 上一篇    下一篇

多模式镇痛用于开颅术后切口局部疼痛疗效观察

陆菁菁1a;于书卿1b;钱柯1b;王集生1b   

  1. 1.首都医科大学附属北京天坛医院,a.神经内科; b.神经外科,北京市 100050
  • 收稿日期:2009-05-19 出版日期:2009-07-01 发布日期:2009-07-01
  • 通讯作者: 王集生

Effect of Multimodal Analgesia on Incision of Scalp Pain after Craniotomy

LU Jing-jing,YU Shu-qing,QIAN Ke,et al   

  1. Department of Neurology,Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China
  • Received:2009-05-19 Published:2009-07-01 Online:2009-07-01

摘要: 目的 观察神经外科开颅患者术后切口局部疼痛的临床特点,并探讨氨酚羟考酮多模式镇痛的临床效果和不良反应。方法 129例择期开颅手术的神经外科患者,记录术后1周内头痛的发生时间、部位、强度和性质。确诊切口局部疼痛后,分别给予氨酚羟考酮(治疗组)或罗痛定(对照组)口服。结果 开颅术后患者1周内切口局部中-重度疼痛发生率为39.5%(51/129)。治疗组疼痛缓解显效率为76.9%(20/26),对照组为36.0%(9/25)(P<0.01); 治疗组疼痛强度差明显高于对照组(P<0.01); 应用氨酚羟考酮后未出现严重不良反应。结论 切口局部中-重度疼痛是开颅术后较为常见的并发症,氨酚羟考酮对其具有良好的疗效。

关键词: 多模式镇痛, 羟考酮, 对乙酰氨基酚, 术后疼痛, 颅脑手术

Abstract: Objective To explore the clinical features and the management of incision of scalp pain after craniotomy. Methods 129 patients after craniotomy without postoperative neuralgia were involved. The onset, severity, and characteristics of the pain were recorded within 1 week after the craniotomy. Patients with moderate-severe pain were given oxycodone and acetaminophen (treatment group) or rotundine (control) for 3 d. Results 39.5%(51/129)of patients experienced moderate to severe postoperative pain. After treatment, 76.9% (20/26) in treatment group and 36.0% (9/25) in control were released from the pain (P<0.01). The pain intensity differences and sum of pain intensity differences were more in treatment than in control (P<0.01). Conclusion Incision of scalp pain is common after craniotomy. Oxycodone and acetaminophen, called multimodal analgesia is efficacious and safe for it.

Key words: multimodal analgesia, oxycodone, acetaminophen, postoperative pain, craniotomy