《中国康复理论与实践》

《中国康复理论与实践》 ›› 2009, Vol. 15 ›› Issue (11): 1058-1060.

• 临床研究 • 上一篇    下一篇

重复经颅磁刺激对不完全性脊髓损伤患者的干预效果

潘钰1;汪漩2;杜巨豹1;霍速1;周景升1;杨远滨1;屈亚萍1;刘霖1;朱琳1;宋为群1;王茂斌1   

  1. 1.首都医科大学宣武医院康复医学科，北京市 100053;2.首都医科大学生理学系，北京市 100069
  • 收稿日期:2009-08-05 出版日期:2009-11-01 发布日期:2009-11-01

Effect of Repetitive Transcranial Magnetic Stimulation on Incomplete Spinal Cord Injury

PAN Yu,WANG Xuan,DU Ju-bao,et al   

  1. Capital Medical University Xuanwu Hospital, Beijing 100053,China
  • Received:2009-08-05 Published:2009-11-01 Online:2009-11-01

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摘要： 目的 观察重复经颅磁刺激（rTMS）对不完全性脊髓损伤患者运动功能的影响。方法 22例T5～T12节段脊髓损伤患者（ASCI C级）随机分为rTMS 组和对照组。12例rTMS组患者于Cz部位给予磁刺激，并接受康复训练；10例对照组患者仅进行康复训练。治疗前后比较ASIA运动评分、轻触觉评分、针刺觉评分，抗重力体位双下肢主动关节活动度（ROM），脊髓损伤步行指数Ⅱ（WISCIⅡ）和功能独立性评定（FIM）。结果 rTMS组和对照组患者治疗前临床评价指标均无显著性差异（P>0.05）；两组治疗后ASIA运动评分、双下肢ROM、FIM评分均有改善（P<0.05）；rTMS组治疗后WISCIⅡ也有改善（P<0.05），且ASIA运动评分高于对照组（P<0.05）。结论 rTMS可促进不完全性脊髓损伤患者的运动功能改善，提高步行功能。

关键词: 脊髓损伤, 重复经颅磁刺激（rTMS）, 运动功能, 康复

Abstract: Objective To investigate the effects of repetitive transcranial magnetic stimulation (rTMS) on motor recovery in patients with incomplete spinal cord injury （SCI）. Methods 22 patients with T5～T12 incomplete spinal cord injury (ASIA C) were randomly divided into rTMS group and control group. 12 ptients in rTMS group were treated with 10Hz rTMS （10×5 s with 2 min interval) on motor cortex and rehabilitation. 10 patients in control group treated with rehabilitation only. They were assessed with ASIA motor score, ASIA pin prick score, ASIA light touch score, range of motion (ROM) of legs in antigravitation position, walking index for spinal cord injury Ⅱ (WISCIⅡ) and functional independence measure (FIM) score before and 4 weeks after treatment. Results There was no difference between two groups with the clinical assessment before treatment （P>0.05）. The ASIA motor score, ROM of legs and FIM score improved in both groups after treatment （P<0.05）. The score of WISCIⅡ also improved in rTMS group （P<0.05）, and ASIA motor score improved more in rTMS group than that of control group （P<0.05）. Conclusion rTMS can facilitate the recovery of the motor and walking function in patient with incomplete spinal cord injury.

Key words: spinal cord injury, repetitive transcranial magnetic stimulation, motor function, rehabilitation