《中国康复理论与实践》

《中国康复理论与实践》 ›› 2009, Vol. 15 ›› Issue (11): 1071-1073.

• 临床观察 • 上一篇    下一篇

脑干胶质瘤的病理、临床与预后

王军梅1;崔云1;张力伟2;罗麟1;李桂林1   

  1. 1.首都医科大学北京市神经外科研究所神经病理科，北京市 100050;2.首都医科大学附属北京天坛医院神经外科，北京市 100050
  • 收稿日期:2009-03-11 出版日期:2009-11-01 发布日期:2009-11-01
  • 通讯作者: 李桂林

Clinical and Pathologic Features of Brainstem Gliomas Associated with Outcome: 54 Cases Report

WANG Jun-mei,CUI Yun,ZHANG Li-wei,et al   

  1. Beijing Neurosurgery Institution, Capital Medical University, Beijing 100050, China
  • Received:2009-03-11 Published:2009-11-01 Online:2009-11-01

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摘要： 目的 探讨病理形态学及其他因素对脑干胶质瘤预后判断的意义。方法 对54例脑干胶质瘤患者进行回顾性分析及随访。结果和结论 41例获得随访，首发症状为声音嘶哑、饮水呛咳或头晕；肿瘤级别高，形态学显示有坏死、核分裂象多、血管内皮增生以及Ki-67增殖指数＞5%与生存率低有关，Rosenthal纤维多出现在低级别胶质瘤中，与较高生存率有关。

关键词: 胶质瘤, 脑干, 预后, 病理, Ki-67

Abstract: Objective To scan significant clinicopathologic parameters in brainstem gliomas (BG) for outcome. Methods 54 cases with BG were reviewed and followed up. Results and Conclusion 41 cases were followed up. The main complaint included hoarseness and bucking, dizziness. The higher tumor grade, higher mitotic-index, necrosis of tumor, hyperplasy of blood vessel endothelium, Ki-67 index > 5% were associated with shorter survival. In opposite, Rosenthal fibers always presented in lower grade gliomas and associated with long survival.

Key words: gliomas, brainstem, outcome, pathology, Ki-67